375853-82-0

• 常用中文名：1,2,3,6-四氢吡啶-4-硼酸频哪醇酯
• 常用英文名：1,2,3,6-Tetrahydropyridine-4-boronic acid pinacol ester
• CAS号：375853-82-0
• 分子式：C₁₁H₂₀BNO₂
• 分子量：209.09300
• 发布时间：2018-12-24 16:27:41
• 更新时间：2026-08-08 18:31:29

名称

• 中文名: 1,2,3,6-四氢吡啶-4-硼酸频那醇酯
• 英文名: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine
• 中文别名: 1,2,3,6-四氢-4-(4,4,5,5-四甲基-1,3,2-二氧杂环戊硼烷-2-基)吡啶; 1,2,3,6-四氢-4-(4,4,5,5-四甲基-1,3,2-二氧硼杂环戊烷-2-基)吡啶
• 英文别名: 4-(4,4,5,5-TetraMethyl-[1,3,2]dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; Pyridine,1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl); Pyridine, 1,2,3,6-tetrahydro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl); (1,2,3,6-TETRAHYDROPYRIDIN-4-YL)BORONIC ACID PINACOL ESTER; 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate; TERT-BUTYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDRO-1(2H)-PYRIDINECARBOXYLATE; (N-tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester; 1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1,2,3,6-TETRAHYDROPYRIDINE-4-YL-BORONIC ACID PINACOL ESTER; 1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl); 1,2,3,6-Tetrahydropyridine-4-yl-boronic acid picol ester; N-boc-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine; 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecboxylate; tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydro-1-pyridinecarboxylate

物化性质

• 密度: 0.99
• 沸点: 246ºC
• 分子式: C₁₁H₂₀BNO₂
• 分子量: 209.09300
• 闪点: 103℃
• 精确质量: 209.15900
• PSA: 30.49000
• LogP: 1.86630
• 折射率: 1.477
• 储存条件: -20℃，避光

安全

• 海关编码: 2934999090

合成路线

138647-49-1 73183-34-3 ~98% 375853-82-0

文献：SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE; DUKE UNIVERSITY; PINKERTON, Anthony; MALONEY, Patrick; HERSHBERGER, Paul; PEDDIBHOTLA, Satyamaheshwar; HEDRICK, Michael; BARAK, Lawrence; CARON, Marc Patent: WO2014/100501 A1, 2014 ; Location in patent: Paragraph 00727; 00728 ;

79099-07-3 73183-34-3 ~97% 375853-82-0

文献：Yoshizumi, Takashi; Takahashi, Hirobumi; Miyazoe, Hiroshi; Sugimoto, Yuichi; Tsujita, Tomohiro; Kato, Tetsuya; Ito, Hirokatsu; Kawamoto, Hiroshi; Hirayama, Mioko; Ichikawa, Daisuke; Azuma-Kanoh, Tomoko; Ozaki, Satoshi; Shibata, Yoshihiro; Tani, Takeshi; Chiba, Masato; Ishii, Yasuyuki; Okuda, Shoki; Tadano, Kiyoshi; Fukuroda, Takahiro; Okamoto, Osamu; Ohta, Hisashi Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 4021 - 4029

10221-56-4 138647-49-1 ~79% 375853-82-0

文献：Kim, Eunkyung; Park, Chan Sun; Han, Taedong; Bae, Myung-Ho; Chong, Wonee; Lee, Choong Hyun; Shin, Young Ah; Ahn, Byung-Nak; Kim, Mi Kyung; Shin, Chang Yell; Son, Moon Ho; Kim, Jin Kwan; Moon, Ho Sang; Shim, Hyun Joo; Kim, Eun Jung; Kim, Soon Hoe; Lim, Joong In; Lee, Chun Ho Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 18 p. 4993 - 4996

79099-07-3 ~% 375853-82-0

文献：WO2012/37132 A1, ; WO 2012/037132 A1

41979-39-9 ~% 375853-82-0

文献：US2013/150407 A1, ;

24424-99-5 ~% 375853-82-0

文献：US2013/150407 A1, ;

上下游产品

上游产品  6
138647-49-1 73183-34-3 79099-07-3 10221-56-4
41979-39-9 24424-99-5
下游产品  10
1089280-53-4 885693-48-1 37656-48-7 1121057-75-7
110878-71-2 170011-57-1 1048970-17-7 1198408-35-3
1233145-65-7 1227068-67-8

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%