1089280-53-4

• 常用中文名：tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate
• 常用英文名：tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate
• CAS号：1089280-53-4
• 分子式：C₁₇H₂₆N₂O₃
• 分子量：306.40000
• 发布时间：2017-04-11 02:01:29
• 更新时间：2024-03-03 22:06:12

名称

• 英文名: tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate
• 英文别名: 1,1-dimethylethyl 4-[4-amino-3-(methyloxy)phenyl]-1-piperidine carboxylate; 1-Piperidinecarboxylic acid,4-(4-amino-3-methoxyphenyl)-,1,1-dimethylethyl ester; D-1291

物化性质

• 分子式: C₁₇H₂₆N₂O₃
• 分子量: 306.40000
• 精确质量: 306.19400
• PSA: 64.79000
• LogP: 3.91100

合成路线

1233145-65-7 ~10% 1089280-53-4

文献：SANOFI Patent: US2012/277220 A1, 2012 ; Location in patent: Page/Page column 17 ;

6627-53-8 375853-82-0 ~80% 1089280-53-4

文献：Kuntz, Kevin; Uehling, David Edward; Waterson, Alex Gregory; Emmitte, Kyle Allen; Stevens, Kirk; Shotwell, John Brad; Smith, Stephon Cornell; Nailor, Kristen E.; Salovich, James M.; Wilson, Brian John; Cheung, Mui; Mook, Robert Anthony; Baum, Erich W.; Moorthy, Ganesh Patent: US2008/300242 A1, 2008 ; Location in patent: Page/Page column 109 ; US 20080300242 A1

1246533-06-1 ~% 1089280-53-4

文献：ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; WU, Fengchun; SHEN, Yan; LIU, Cuihua; ZOU, Zhenguang Patent: WO2012/97684 A1, 2012 ; Location in patent: Page/Page column 119-120 ; WO 2012/097684 A1

375853-82-0 ~% 1089280-53-4

文献：ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang Patent: WO2012/97682 A1, 2012 ;

59557-91-4 ~% 1089280-53-4

文献：ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang Patent: WO2012/97682 A1, 2012 ;

103966-66-1 ~% 1089280-53-4

文献：SANOFI Patent: US2012/277220 A1, 2012 ;

321-23-3 ~% 1089280-53-4

文献：SANOFI Patent: US2012/277220 A1, 2012 ;

59557-91-4 375853-82-0 ~% 1089280-53-4

文献：ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; WU, Fengchun; SHEN, Yan; LIU, Cuihua; ZOU, Zhenguang Patent: WO2012/97684 A1, 2012 ; WO 2012/097684 A1

6627-53-8 ~% 1089280-53-4

文献：Mesaros, Eugen F.; Thieu, Tho V.; Wells, Gregory J.; Zificsak, Craig A.; Wagner, Jason C.; Breslin, Henry J.; Tripathy, Rabindranath; Diebold, James L.; McHugh, Robert J.; Wohler, Ashley T.; Quail, Matthew R.; Wan, Weihua; Lu, Lihui; Huang, Zeqi; Albom, Mark S.; Angeles, Thelma S.; Wells-Knecht, Kevin J.; Aimone, Lisa D.; Cheng, Mangeng; Ator, Mark A.; Ott, Gregory R.; Dorsey, Bruce D. Journal of Medicinal Chemistry, 2012 , vol. 55, # 1 p. 115 - 125

上下游产品

上游产品  6
1233145-65-7 6627-53-8 375853-82-0 59557-91-4
103966-66-1 321-23-3
下游产品  0