81907-82-6

• 常用中文名：5-hydroxy Propranolol
• 常用英文名：5-hydroxy Propranolol
• CAS号：81907-82-6
• 分子式：C₁₆H₂₁NO₃
• 分子量：275.34300
• 发布时间：2016-09-23 10:53:12
• 更新时间：2023-01-16 19:59:31
• 5-hydroxy Propranolol is a metabolite of propranolol , a β-adrenergic receptor antagonist.

名称

• 英文名: 5-[2-Hydroxy-3-(isopropylamino)propoxy]-1-naphthol
• 英文别名: 2-Piperidinecarboxylic acid,5-hydroxy; 5-Hydroxy-pipecolinsaeure; 5-hydroxy-L-pipecolic acid; optically inactive 5-hydroxy-piperidine-2-carboxylic acid; 5-Hydroxypropranolol; 5-Hydroxypipecolic acid; opt.-inakt. 5-Hydoxy-piperidin-2-carbonsaeure; 5-hydroxy-piperidine-2-carboxylic acid

物化性质

• 密度: 1.169g/cm3
• 沸点: 487.526ºC at 760 mmHg
• 分子式: C₁₆H₂₁NO₃
• 分子量: 275.34300
• 闪点: 248.647ºC
• 精确质量: 275.15200
• PSA: 61.72000
• LogP: 2.67400
• 折射率: 1.602
• 储存条件: -20°C，密闭，干燥

合成路线

525-66-6 ~20% 81907-82-6

文献：Kinne, Matthias; Poraj-Kobielska, Marzena; Aranda, Elisabet; Ullrich, Rene; Hammel, Kenneth E.; Scheibner, Katrin; Hofrichter, Martin Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 11 p. 3085 - 3087

318-98-9 ~% 10476-53-6 30200-48-7 10476-54-7 详细

文献：Ghabrial; Nand; Stead; Smallwood; Morgan Journal of Pharmaceutical Sciences, 1994 , vol. 83, # 7 p. 931 - 936

3588-80-5 ~% 81907-82-6

文献：Oatis Jr.; Russell; Knapp; Walle Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 309 - 314