86954-05-4

• 常用中文名：Cbz-DL-脯氨醇
• 常用英文名：Benzyl 2-(hydroxymethyl)-1-pyrrolidinecarboxylate
• CAS号：86954-05-4
• 分子式：C₁₃H₁₇NO₃
• 分子量：235.279
• 发布时间：2018-08-12 05:29:31
• 更新时间：2025-08-23 11:47:15

名称

• 中文名: Cbz-DL-脯氨醇
• 英文名: benzyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate
• 英文别名: N-<(Benzyloxy)carbonyl>-2-(hydroxymethyl)pyrrolidine; Cbz-DL-Prolinol; (2S)-1-(Benzyloxycarbonyl)-2-hydroxymethyl pyrrolidine; 1-Pyrrolidinecarboxylic acid, 2-(hydroxymethyl)-, phenylmethyl ester; 2-Hydroxymethyl-pyrrolidine-1-carboxylic acid benzyl ester; R-N-(benzyloxycarbonyl)-2-pyrrolidinemethanol; (R)-2-hydroxymethyl-1-pyrrolidine carboxylic acid phenylmethyl ester; (S)-2-hydroxymethyl-1-pyrrolidine carboxylic acid phenylmethyl ester; N-carbobenzyloxy-2-hydroxymethyl pyrrolidine; 1-Benzyloxycarbonyl-2-pyrrolidinemethanol; Benzyl 2-(hydroxymethyl)-1-pyrrolidinecarboxylate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 382.0±25.0 °C at 760 mmHg
• 分子式: C₁₃H₁₇NO₃
• 分子量: 235.279
• 闪点: 184.8±23.2 °C
• 精确质量: 235.120850
• PSA: 49.77000
• LogP: 1.07
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.561

安全

• 海关编码: 2933990090

合成路线

1148-11-4 ~92% 86954-05-4

文献：Mori, Miwako; Washioka, Yumiko; Urayama, Takao; Yoshiura, Kagari; Chiba, Katsumi; Ban, Yoshio Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4058 - 4067

501-53-1 498-63-5 ~96% 86954-05-4

文献：Boto, Alicia; Hernandez, Dacil; Hernandez, Rosendo; Montoya, Adriana; Suarez, Ernesto European Journal of Organic Chemistry, 2007 , # 2 p. 325 - 334

103108-59-4 ~94% 86954-05-4

文献：Fukuyama, Tohru; Laird, Alison A.; Hotchkiss, Lia M. Tetrahedron Letters, 1985 , vol. 26, # 51 p. 6291 - 6292

1885-14-9 498-63-5 ~% 86954-05-4

文献：Merck and Co., Inc. Patent: US6498165 B1, 2002 ; US 6498165 B1

68832-13-3 501-53-1 ~% 86954-05-4

文献：E. R. Squibb and Sons, Inc. Patent: US4902684 A1, 1990 ;

112380-58-2 498-63-5 ~93% 86954-05-4

文献：Takeda, Kazuyoshi; Tsuboyama, Kanoko; Hoshino, Mitsuho; Kishino, Miyuki; Ogura, Haruo Synthesis, 1987 , # 6 p. 557 - 560

上下游产品

上游产品  6
1148-11-4 501-53-1 498-63-5 1885-14-9
68832-13-3 112380-58-2
下游产品  1
69261-54-7

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%