162504-75-8

• 常用中文名：1-BOC-4-哌啶丙酸甲酯
• 常用英文名：Methyl N-Boc-4-piperidinepropionate
• CAS号：162504-75-8
• 分子式：C₁₄H₂₅NO₄
• 分子量：271.353
• 发布时间：2018-07-09 20:47:20
• 更新时间：2024-01-10 19:46:52

名称

• 中文名: 1-BOC-4-哌啶丙酸甲酯
• 英文名: methyl n-boc-4-piperidinepropionate
• 中文别名: N-叔丁氧羰基-4-哌啶基丙酸甲酯; N-Boc-4-哌啶丙酸甲酯; N-BOC-4-哌啶基丙酸甲酯
• 英文别名: 4-Piperidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; tert-Butyl 4-(3-methoxy-3-oxopropyl)piperidine-1-carboxylate; 2-(2-Methyl-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-4-piperidinyl)propanoic acid; 2-Methyl-2-propanyl 4-(3-methoxy-3-oxopropyl)-1-piperidinecarboxylate; 1-Boc-4-Piperidinylpropionic Acid Methyl Ester; Methyl N-Boc-4-piperidinepropionate; 4-Piperidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-α,2-dimethyl-; N-BOC-4-PIPERIDINYLPROPIONIC ACID METHYL ESTER; MethylN-Boc-4-piperidinepropionate

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 387.1±15.0 °C at 760 mmHg
• 分子式: C₁₄H₂₅NO₄
• 分子量: 271.353
• 闪点: 187.9±20.4 °C
• 精确质量: 271.178345
• PSA: 55.84000
• LogP: 2.16
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.481
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933399090

合成路线

194933-85-2 ~99% 162504-75-8

文献：Klein, Scott I.; Molino, Bruce F.; Czekaj, Mark; Gardner, Charles J.; Chu, Valeria; Brown, Karen; Sabatino, Ralph D.; Bostwick, Jeffrey S.; Kasiewski, Charles; Bentley, Ross; Windisch, Vincent; Perrone, Mark; Dunwiddie, Christopher T.; Leadley, Robert J. Journal of Medicinal Chemistry, 1998 , vol. 41, # 14 p. 2492 - 2502

365998-55-6 ~% 162504-75-8

文献：WO2004/58702 A2, ; Page 35; 21 ; WO 2004/058702 A2

154775-43-6 74-88-4 ~% 162504-75-8

文献：WO2004/92124 A2, ; Page 83 ; WO 2004/092124 A2

186581-53-3 154775-43-6 ~% 162504-75-8

文献：WO2008/141976 A1, ; Page/Page column 39 ; WO 2008/141976 A1

24424-99-5 ~% 162504-75-8

文献：Journal of Medicinal Chemistry, , vol. 41, # 14 p. 2492 - 2502

84358-13-4 ~% 162504-75-8

文献：Journal of Medicinal Chemistry, , vol. 41, # 14 p. 2492 - 2502

139290-70-3 ~% 162504-75-8

文献：Journal of Medicinal Chemistry, , vol. 41, # 14 p. 2492 - 2502

137076-22-3 ~% 162504-75-8

文献：Journal of Medicinal Chemistry, , vol. 41, # 14 p. 2492 - 2502

498-94-2 ~% 162504-75-8

文献：Journal of Medicinal Chemistry, , vol. 41, # 14 p. 2492 - 2502

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%