460748-84-9

• 常用中文名：(S)-2-(氟甲基)吡咯烷-1-羧酸叔丁酯
• 常用英文名：2-Methyl-2-propanyl (2S)-2-(fluoromethyl)-1-pyrrolidinecarboxylat e
• CAS号：460748-84-9
• 分子式：C₁₀H₁₈FNO₂
• 分子量：203.25400
• 发布时间：2018-12-18 12:27:03
• 更新时间：2025-09-26 13:27:20

名称

• 中文名: (S)-2-(氟甲基)吡咯烷-1-羧酸叔丁酯
• 英文名: 2-Methyl-2-propanyl (2S)-2-(fluoromethyl)-1-pyrrolidinecarboxylat e
• 英文别名: tert-butyl (2S)-2-(fluoromethyl)-1-pyrrolidinecarboxylate; N-BOC-(2S)-2-cyanomethyl-1-pyrrolidine; (S)-N-Boc-pyrrolidylacetonitrile; N-BOC-(2S)-PYRR(2-CHCN); tert-butyl (S)-2-cyanomethylpyrrolidine-1-carboxylate; 2S-Cyanomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester; N-Boc-2R-cyanomethyl pyrrolidine; (S)-TERT-BUTYL 2-(CYANOMETHYL)PYRROLIDINE-1-CARBOXYLATE; tert-butyl (2S)-2-(fluoromethyl)pyrrolidine-1-carboxylate

物化性质

• 分子式: C₁₀H₁₈FNO₂
• 分子量: 203.25400
• 精确质量: 203.13200
• PSA: 29.54000
• LogP: 2.29330

合成路线

69610-40-8 ~12% 460748-84-9

文献：BANYU PHARMACEUTICAL CO., LTD. Patent: EP1741703 A1, 2007 ; Location in patent: Page/Page column 90 ; EP 1741703 A1

86661-32-7 ~79% 460748-84-9

文献：Krause-Heuer, Anwen M.; Howell, Nicholas R.; Matesic, Lidia; Dhand, Geetanjali; Young, Emma L.; Burgess, Leena; Jiang, Cathy D.; Lengkeek, Nigel A.; Fookes, Christopher J. R.; Pham, Tien Q.; Sobrio, Franck; Greguric, Ivan; Fraser, Benjamin H. MedChemComm, 2013 , vol. 4, # 2 p. 347 - 352

23356-96-9 ~% 460748-84-9

文献：Krause-Heuer, Anwen M.; Howell, Nicholas R.; Matesic, Lidia; Dhand, Geetanjali; Young, Emma L.; Burgess, Leena; Jiang, Cathy D.; Lengkeek, Nigel A.; Fookes, Christopher J. R.; Pham, Tien Q.; Sobrio, Franck; Greguric, Ivan; Fraser, Benjamin H. MedChemComm, 2013 , vol. 4, # 2 p. 347 - 352

24424-99-5 ~% 460748-84-9

文献：Krause-Heuer, Anwen M.; Howell, Nicholas R.; Matesic, Lidia; Dhand, Geetanjali; Young, Emma L.; Burgess, Leena; Jiang, Cathy D.; Lengkeek, Nigel A.; Fookes, Christopher J. R.; Pham, Tien Q.; Sobrio, Franck; Greguric, Ivan; Fraser, Benjamin H. MedChemComm, 2013 , vol. 4, # 2 p. 347 - 352

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