478832-21-2

• 常用中文名：4-羟基氮杂环庚烷-1-羧酸叔丁酯
• 常用英文名：2-Bromo-4-phenylpyrimidine
• CAS号：478832-21-2
• 分子式：C₁₀H₇BrN₂
• 分子量：235.080
• 发布时间：2018-11-28 16:29:35
• 更新时间：2025-08-25 17:03:37

名称

• 中文名: 4-羟基氮杂环庚烷-1-羧酸叔丁酯
• 英文名: tert-butyl 4-hydroxyazepane-1-carboxylate
• 中文别名: 1-叔丁氧羰基-4-羟基氮杂环庚烷; N-Boc-4-羟基氮杂环庚烷; N-Boc-4--氮杂卓醇; 1-BOC-4-羟基氮杂环庚烷; N-Boc-4-氮杂卓醇
• 英文别名: N-(tert-butoxycarbonyl)-4-azepanol; 2-Bromo-4-phenylpyrimidine; 1,1-dimethylethyl 4-hydroxyazepane-1-carboxylate; 4-Hydroxyazepane-1-carboxylic acid tert-butyl ester; 1,1-dimethylethyl 4-hydroxyhexahydro-1H-azepine-1-carboxylate; 1-Boc-4-Hydroxyazepane; Pyrimidine, 2-bromo-4-phenyl-; N-Boc-Hexahydro-1H-azepin-4-ol

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 389.1±35.0 °C at 760 mmHg
• 分子式: C₁₀H₇BrN₂
• 分子量: 235.080
• 闪点: 189.1±25.9 °C
• 精确质量: 233.979248
• PSA: 25.78000
• LogP: 2.41
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.612
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

109162-29-0 34619-03-9 ~67% 478832-21-2

文献：Sumitomo Pharmaceuticals Company, Limited Patent: EP1403255 A1, 2004 ; Location in patent: Page 93-94 ; EP 1403255 A1

188975-88-4 ~99% 478832-21-2

文献：ELI LILLY AND COMPANY Patent: WO2009/12125 A1, 2009 ; Location in patent: Page/Page column 30 ;

39888-51-2 24424-99-5 ~70% 478832-21-2

文献：Sumitomo Pharmaceuticals Company, Limited Patent: EP1500643 A1, 2005 ; Location in patent: Page 48 ; EP 1500643 A1

24424-99-5 ~% 478832-21-2

文献：JANSSEN RandD IRELAND; GUILLEMONT, Jerôme, Emile, Georges; LANÇOIS, David, Francis, Alain; MOTTE, Magali, Madeleine, Simone; KOUL, Anil; BALEMANS, Wendy, Mia, Albert Patent: WO2013/21051 A1, 2013 ; WO 2013/021051 A1

上下游产品

上游产品  5
109162-29-0 34619-03-9 188975-88-4 39888-51-2
24424-99-5
下游产品  2
1159823-34-3 188975-88-4

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%