3571-71-9

• 常用中文名：美他特罗
• 常用英文名：metaterol
• CAS号：3571-71-9
• 分子式：C₁₁H₁₇NO₂
• 分子量：195.26
• 相关类别： 信号通路 G 蛋白偶联受体/G 蛋白 肾上腺素能受体
• 发布时间：2018-02-28 08:00:00
• 更新时间：2025-08-26 21:24:51
• Metaterol 是一种 β-肾上腺素能受体 (beta-adrenergic receptor) 激动剂。

名称

• 中文名: 美他特罗
• 英文名: 3-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenol
• 英文别名: Isopropylnoradrianol; EINECS 222-678-9; Metaterol

物化性质

• 密度: 1.099g/cm3
• 沸点: 355.9ºC at 760mmHg
• 分子式: C₁₁H₁₇NO₂
• 分子量: 195.26
• 闪点: 143ºC
• 精确质量: 195.12600
• PSA: 52.49000
• LogP: 1.81450
• 折射率: 1.55

生物活性

• 描述: Metaterol 是一种 β-肾上腺素能受体 (beta-adrenergic receptor) 激动剂。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体
• 靶点:

  β adrenergic receptor

• 参考文献:

  [1]. Bilezikian JP, et al. Structure-binding-activity analysis of beta-adrenergic amines--I. Binding to the beta receptor and activation of adenylate cyclase. Biochem Pharmacol. 1978 May 15;27(10):1445-54.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DO6526000 CHEMICAL NAME : Benzyl alcohol, m-hydroxy-alpha-((isopropylamino)methyl)- CAS REGISTRY NUMBER : 3571-71-9 BEILSTEIN REFERENCE NO. : 2805325 LAST UPDATED : 199712 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C11-H17-N-O2 MOLECULAR WEIGHT : 195.29 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,297,1947

安全

• 海关编码: 2922509090

合成路线

20697-05-6 ~% 3571-71-9

文献：Alpatova, T. A.; Kulinskii, V. I.; Yashunskii, V. G. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 8 p. 543 - 546 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 8 p. 922 - 925

7562-37-0 ~% 3571-71-9

文献：Alpatova, T. A.; Kulinskii, V. I.; Yashunskii, V. G. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 8 p. 543 - 546 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 8 p. 922 - 925

2491-37-4 ~% 3571-71-9

文献：Corrigan et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 6258

20938-84-5 ~% 3571-71-9

文献：Alpatova, T. A.; Kulinskii, V. I.; Yashunskii, V. G. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 8 p. 543 - 546 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 8 p. 922 - 925

90005-54-2 ~% 3571-71-9

文献：D'Amico et al. Chimica e l'Industria (Milan, Italy), 1956 , vol. 38, p. 93,98

857561-03-6 ~% 3571-71-9

文献：D'Amico et al. Chimica e l'Industria (Milan, Italy), 1956 , vol. 38, p. 93,98

536-21-0 67-64-1 ~% 3571-71-9

文献：D'Amico et al. Chimica e l'Industria (Milan, Italy), 1956 , vol. 38, p. 93,98

海关

海关编码	2922509090
中文概述	2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	R.进口食品卫生监督检验 S.出口食品卫生监督检验
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%