5033-28-3

• 常用中文名：4-氯-N-羟基苯羧酰亚胺
• 常用英文名：4-Chloro-N-hydroxybenzenecarboximidamide
• CAS号：5033-28-3
• 分子式：C₇H₇ClN₂O
• 分子量：170.596
• 发布时间：2018-04-14 08:00:00
• 更新时间：2024-01-10 00:41:32

名称

• 中文名: 4-氯-N-羟基苯羧酰亚胺
• 英文名: 4-Chloro-N-hydroxybenzimidamide
• 英文别名: Benzenecarboximidamide, 4-chloro-N-hydroxy-; 4-CHLOROBENZAMIDOXIME; MFCD00029674; 4-Chloro-N-hydroxybenzenecarboximidamide; 4-CHLORO-N'-HYDROXYBENZENECARBOXIMIDAMIDE; (Z)-4-Chloro-N'-hydroxybenzamidine; 4-CHLORO-N'-HYDROXYBENZENECARBOXYMIDAMIDE

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 334.6±44.0 °C at 760 mmHg
• 熔点: 129ºC
• 分子式: C₇H₇ClN₂O
• 分子量: 170.596
• 闪点: 156.2±28.4 °C
• 精确质量: 170.024689
• PSA: 58.61000
• LogP: 1.91
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.600
• 储存条件: 2-8°C，密封，干燥

MSDS

Name: 4-Chloro-N -hydroxybenzenecarboximidamide 95+% Material Safety Data Sheet Synonym: 4-Chlorobenzamide oxim CAS: 5033-28-3 Section 1 - Chemical Product MSDS Name:4-Chloro-N -hydroxybenzenecarboximidamide 95+% Material Safety Data Sheet Synonym:4-Chlorobenzamide oxim Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 5033-28-3 4-Chloro-N'-hydroxybenzenecarboximidam 95+% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 5033-28-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 129 - 132 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H7ClN2O Molecular Weight: 171 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, bases, acids. Hazardous Decomposition Products: Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 5033-28-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 4-Chloro-N'-hydroxybenzenecarboximidamide - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 5033-28-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 5033-28-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 5033-28-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S37/39
• 海关编码: 2925290090

合成路线

623-03-0 ~98% 5033-28-3

文献：PFIZER INC. Patent: EP795328 A1, 1997 ; EP 0795328 A1 Title/Abstract Full Text Show Details Pfizer Inc. Patent: US5821245 A1, 1998 ; Title/Abstract Full Text Show Details Pfizer Inc. Patent: US6166020 A1, 2000 ; US 6166020 A

140-53-4 ~% 5033-28-3

文献：Chevron Research Company Patent: US4584317 A1, 1986 ;

172469-60-2 ~96% 5033-28-3

文献：Ogurtsov, V. A.; Rakitin, O. A.; Strelenko, Yu. A.; Obruchnikova, N. V.; Khmel'nitskii, L. I. Russian Chemical Bulletin, 1993 , vol. 42, # 4 p. 706 - 708 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 4 p. 742 - 743

15500-74-0 ~2% 5033-28-3 172469-60-2

文献：Ogurtsov, V. A.; Rakitin, O. A.; Strelenko, Yu. A.; Obruchnikova, N. V.; Khmel'nitskii, L. I. Russian Chemical Bulletin, 1993 , vol. 42, # 4 p. 706 - 708 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 4 p. 742 - 743

766-84-7 ~% 5033-28-3

文献：Adib, Mehdi; Jahromi, Amin Haghighat; Tavoosi, Narjes; Mahdavi, Mohammad; Bijanzadeh, Hamid Reza Tetrahedron Letters, 2006 , vol. 47, # 17 p. 2965 - 2967

15500-74-0 ~% 5033-28-3

文献：Ogurtsov, V. A.; Rakitin, O. A.; Strelenko, Yu. A.; Obruchnikova, N. V.; Khmel'nitskii, L. I. Russian Chemical Bulletin, 1993 , vol. 42, # 4 p. 706 - 708 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 4 p. 742 - 743

28123-63-9 ~% 5033-28-3

文献：Truce,W.E.; Naik,A.R. Canadian Journal of Chemistry, 1966 , vol. 44, p. 297 - 305

503027-47-2 15500-74-0 ~3% 5033-28-3 172469-60-2

文献：Ogurtsov, V. A.; Rakitin, O. A.; Strelenko, Yu. A.; Obruchnikova, N. V.; Khmel'nitskii, L. I. Russian Chemical Bulletin, 1993 , vol. 42, # 4 p. 706 - 708 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 4 p. 742 - 743

上下游产品

上游产品  5
623-03-0 140-53-4 15500-74-0 766-84-7
28123-63-9
下游产品  10
5372-40-7 21614-47-1 19932-93-5 623-03-0
619-56-7 57238-75-2 618-39-3 13463-94-0
14401-51-5 30149-93-0

海关

海关编码	2925290090
中文概述	2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%