114088-58-3

• 常用中文名：9-((2-phosphonylmethoxy)ethyl)guanine
• 常用英文名：9-((2-phosphonylmethoxy)ethyl)guanine
• CAS号：114088-58-3
• 分子式：C₈H₁₂N₅O₅P
• 分子量：289.18500
• 发布时间：2016-04-19 22:12:39
• 更新时间：2025-08-25 09:50:06

名称

• 英文名: 2-(2-amino-6-oxo-3H-purin-9-yl)ethoxymethylphosphonic acid
• 英文别名: (2-(2-amino-6-oxo-1,6-dihydropurin-9-yl)ethoxy)methylphosphonic acid; ((2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)ethoxy)methyl)phosphonic acid; PMEG; ((2-(2-amino-6-oxo-1H-purin-9(6H)-yl)ethoxy)methyl)phosphonic acid; 9-((2-Phosphonylmethoxy)ethyl)guanine; 5-(3-Hydroxy-2-phosphonomethoxypropylguanine); Phosphonic acid,((2-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)ethoxy)methyl); 9-(2-(phosphonomethoxy)ethyl)guanine

物化性质

• 密度: 2.03g/cm3
• 沸点: 726.5ºC at 760mmHg
• 分子式: C₈H₁₂N₅O₅P
• 分子量: 289.18500
• 闪点: 393.2ºC
• 精确质量: 289.05800
• PSA: 167.15000
• 蒸汽压: 3.75E-22mmHg at 25°C
• 折射率: 1.803

合成路线

228874-25-7 ~91% 114088-58-3

文献：Jansa, Petr; Baszczynski, Ondrej; Prochazkova, Eliska; Dracinsky, Martin; Janeba, Zlatko Green Chemistry, 2012 , vol. 14, # 8 p. 2282 - 2288

2857-97-8 117087-28-2 ~% 114088-58-3

文献：Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic; Rega Stichting v.z.w. Patent: US5650510 A1, 1997 ;

142613-53-4 ~72% 114088-58-3

文献：Yu; Bronson; Yang; Patick; Alam; Brankovan; Datema; Hitchcock; Martin Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2958 - 2969

340683-37-6 ~% 114088-58-3

文献：Elbert, Tomas; Brehova, Petra; Holy, Antonin Collection of Czechoslovak Chemical Communications, 2010 , vol. 75, # 7 p. 757 - 766

10310-21-1 ~% 114088-58-3

文献：Yu; Bronson; Yang; Patick; Alam; Brankovan; Datema; Hitchcock; Martin Journal of Medicinal Chemistry, 1992 , vol. 35, # 16 p. 2958 - 2969

73-40-5 ~% 114088-58-3

文献：Franchetti; Abu Sheikha; Cappellacci; Messini; Grifantini; Loi; De Montis; Spiga; La Colla Nucleosides and Nucleotides, 1994 , vol. 13, # 8 p. 1707 - 1719

182798-86-3 ~% 114088-58-3

文献：Schinkmanova, Marketa; Votruba, Ivan; Shibata, Riri; Han, Bin; Liu, Xiaohong; Cihlar, Tomas; Holy, Antonin Collection of Czechoslovak Chemical Communications, 2008 , vol. 73, # 2 p. 275 - 291

182798-83-0 ~% 114088-58-3

文献：Schinkmanova, Marketa; Votruba, Ivan; Shibata, Riri; Han, Bin; Liu, Xiaohong; Cihlar, Tomas; Holy, Antonin Collection of Czechoslovak Chemical Communications, 2008 , vol. 73, # 2 p. 275 - 291