1007882-59-8

• 常用中文名：(S)-2-(5-溴-1H-咪唑-2-基)吡咯烷-1-甲酸叔丁酯
• 常用英文名：tert-Butyl (S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
• CAS号：1007882-59-8
• 分子式：C₁₂H₁₈BrN₃O₂
• 分子量：316.194
• 发布时间：2019-01-01 11:13:32
• 更新时间：2025-08-25 09:31:46

名称

• 中文名: (S)-2-(5-溴-1H-咪唑-2-基)-吡咯烷-1-羧酸叔丁酯
• 英文名: tert-butyl (2S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
• 英文别名: PYR239; 2(S)-tert-butyl 2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate; 1-Pyrrolidinecarboxylic acid,2-(5-bromo-1H-imidazol-2-yl)-,1,1-dimethylethyl ester,(2S); 1-Pyrrolidinecarboxylic acid, 2-(5-bromo-1H-imidazol-2-yl)-, 1,1-dimethylethyl ester, (2S)-; 2-Methyl-2-propanyl (2S)-2-(4-bromo-1H-imidazol-2-yl)-1-pyrrolidinecarboxylate; (S)-tert-butyl 2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate; (S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylic acid tert-butyl ester; (S)-tert-Butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate; tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 469.3±35.0 °C at 760 mmHg
• 分子式: C₁₂H₁₈BrN₃O₂
• 分子量: 316.194
• 闪点: 237.6±25.9 °C
• 精确质量: 315.058228
• PSA: 58.22000
• LogP: 1.65
• 外观性状: 白色至黄色固体
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.567
• 储存条件: 2-8°C，密封，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

1007882-58-7 ~30% 1007882-59-8

文献：TIBOTEC PHARMACEUTICALS; VANDYCK, Koen; LAST, Stefaan Julien; HOUPIS, Ioannis Nicolaos; RABOISSON, Pierre Jean-Marie Bernard Patent: WO2011/54834 A1, 2011 ; Location in patent: Page/Page column 35 ;

1240893-76-8 ~% 1007882-59-8

文献：MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ; Location in patent: Example 3 ;

69610-40-8 ~% 1007882-59-8

文献：MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ;

69610-41-9 ~% 1007882-59-8

文献：MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ;

15761-39-4 ~% 1007882-59-8

文献：TIBOTEC PHARMACEUTICALS; VANDYCK, Koen; LAST, Stefaan Julien; HOUPIS, Ioannis Nicolaos; RABOISSON, Pierre Jean-Marie Bernard Patent: WO2011/54834 A1, 2011 ;

1007882-59-8 ~% 1007882-59-8

文献：MERCK SHARP and DOHME CORP.; COBURN, Craig A.; WU, Hao; HU, Bin; ZHONG, Bin; WANG, Dahai; XU, Zaixu; SUN, Fei; JI, Tao; DAN, Zhigang Patent: WO2012/3642 A1, 2012 ;

上下游产品

上游产品  6
1007882-58-7 1240893-76-8 69610-40-8 69610-41-9
15761-39-4 1007882-59-8
下游产品  1
1007882-59-8

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%