138154-39-9

138154-39-9结构式

常用中文名：5-((2-(二乙基氨基)乙基)氨基)-8-羟基-6H-咪唑并[4,5,1-de]吖啶-6-酮
常用英文名：C-1311
CAS号：138154-39-9
分子式：C₂₀H₂₂N₄O₂
分子量：350.41400
发布时间：2018-11-24 08:29:14
更新时间：2024-01-03 18:28:56
Symadex, also known as imidazoacridone; XLS-002 and C-1311, is a member of the novel imidazoacridinone family of anticancer agents. Imidazoacridone has shown activity in experimental tumour models both in vitro and in nude mice. C-1311 at the EC(99) dose delayed progression of cells through the S phase which was followed by G2 arrest. C-1311 does not induce rapid apoptosis in HT-29 cells, instead drug exposure leads to prolonged G2 arrest followed by G2 to M transit and cell death during mitosis in the process of mitotic catastrophe.

中文名	5-((2-(二乙基氨基)乙基)氨基)-8-羟基-6H-咪唑并[4,5,1-de]吖啶-6-酮
英文名	5-((2-(diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4,5,1-de]acridin-6-one
英文别名	5-[[(diethylamino)ethyl]amino]-8-hydroxyimidazo[4,5,1-de]-acridine-6-one C 1311 XLS-002 6H-Imidazo(4,5,1-de)acridin-6-one,5-((2-(diethylamino)ethyl)amino)-8-hydroxy 5-((2-(Diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo(4,5,1-de)acridin-6-one