93738-40-0

• 常用中文名：雷利托林
• 常用英文名：Ralitoline
• CAS号：93738-40-0
• 分子式：C₁₃H₁₃ClN₂O₂S
• 分子量：296.77300
• 发布时间：2018-03-24 08:00:00
• 更新时间：2024-01-14 09:38:16

名称

• 中文名: 雷利托林
• 英文名: (2Z)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-4-oxo-1,3-thiazolidin-2-ylidene)acetamide
• 英文别名: Acetamide,N-(2-chloro-6-methylphenyl)-2-(3-methyl-4-oxo-2-thiazolidinylidene)-,(Z); CI-946; Ralitolinum [Latin]; GOE-4942; Ralitoline; Ralitolina [Spanish]; (Z)-N-(2-Chloro-6-methylphenyl)-(3-methyl-4-oxothiazolidine-2-ylidene)acetamide

物化性质

• 密度: 1.468g/cm3
• 沸点: 522.7ºC at 760mmHg
• 分子式: C₁₃H₁₃ClN₂O₂S
• 分子量: 296.77300
• 闪点: 269.9ºC
• 精确质量: 296.03900
• PSA: 74.71000
• LogP: 2.64440
• 折射率: 1.724

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XJ5132000 CHEMICAL NAME : delta(sup 2,alpha)Thiazolidineaceto-o-toluidide, 6'-chloro-3-methyl-4-oxo-, (Z)- CAS REGISTRY NUMBER : 93738-40-0 LAST UPDATED : 199706 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H13-Cl-N2-O2-S MOLECULAR WEIGHT : 296.79 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1350 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,920,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1350 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,920,1985 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 600 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - other effects REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 51,11,1995 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 1200 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 51,11,1995 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 1800 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities REFERENCE : TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 51,11,1995