63521-85-7

• 常用中文名：依索比星
• 常用英文名：Esorubicin
• CAS号：63521-85-7
• 分子式：C₂₇H₂₉NO₁₀
• 分子量：527.52000
• 发布时间：2018-08-19 11:49:13
• 更新时间：2025-09-17 12:01:48

名称

• 中文名: 依索比星
• 英文名: Esorubicin
• 英文别名: 4'-Deoxyadriamycin; 5,12-Naphthacenedione,10-(2S,4R,6S)-4-aminotetrahydro-6-methyl-2H-pyran-2-yloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-,(8S,10S); 4'-deoxydoxorubicin; 4'-desoxy-doxorubicin

物化性质

• 密度: 1.55g/cm3
• 沸点: 765.8ºC at 760 mmHg
• 分子式: C₂₇H₂₉NO₁₀
• 分子量: 527.52000
• 闪点: 416.9ºC
• 精确质量: 527.17900
• PSA: 185.84000
• LogP: 1.73080
• 折射率: 1.693

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QI9443000 CHEMICAL NAME : 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((tetrahydro-4-amino-6-methyl- 2H-pyran-2-yl) oxy)-8-glycoloyl-1-methoxy-6,8,11-trihydroxy- CAS REGISTRY NUMBER : 63521-85-7 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C27-H29-N-O10 MOLECULAR WEIGHT : 527.57 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 14100 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - rat Cells - not otherwise specified DOSE/DURATION : 340 ug/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 38,167,1989