18740-38-0

• 常用中文名：2,4-二羟基噻吩[2,3-D]嘧啶
• 常用英文名：Thieno[2,3-d]pyrimidine-2,4-diol
• CAS号：18740-38-0
• 分子式：C₆H₄N₂O₂S
• 分子量：168.173
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 羟基嘧啶
• 发布时间：2018-11-26 12:51:11
• 更新时间：2025-08-20 17:16:56
• 下载msds

名称

• 中文名: 2,4-二羟基噻吩[2,3-D]嘧啶
• 英文名: 1H-thieno[2,3-d]pyrimidine-2,4-dione
• 中文别名: 噻吩并[2,3-d]嘧啶-2,4(1h,3h)-二酮
• 英文别名: Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; thieno<2,3-d>pyrimidine-2,4-dione; thieno[2,3-d]pyrimidine-2,4-diol

物化性质

• 密度: 1.5±0.1 g/cm3
• 熔点: 322°C
• 分子式: C₆H₄N₂O₂S
• 分子量: 168.173
• 精确质量: 167.999344
• PSA: 94.48000
• LogP: 0.90
• 折射率: 1.625
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22
• 海关编码: 2934999090

合成路线

1189-71-5 4651-81-4 ~81% 18740-38-0

文献：GENENTECH, INC.; PIRAMED LIMITED; CASTANEDO, Georgette; DOTSON, Jennafer; GOLDSMITH, Richard; GUNZNER, Janet; HEFFRON, Tim; MATHIEU, Simon; OLIVERO, Alan; STABEN, Steven; SUTHERLIN, Daniel P.; TSUI, Vickie; WANG, Shumei; ZHU, Bing-Yan; BAYLISS, Tracy; CHUCKOWREE, Irina; FOLKES, Adrian; WAN, Nan Chi Patent: WO2008/73785 A2, 2008 ; Location in patent: Page/Page column 169 ; WO 2008/073785 A2

4651-81-4 57-13-6 ~64% 18740-38-0

文献：Deng, Jifeng; Peng, Li; Zhang, Guicheng; Lan, Xiaobing; Li, Chufang; Chen, Fuxin; Zhou, Yayao; Lin, Zuoxian; Chen, Ling; Dai, Renke; Xu, Hongjiang; Yang, Ling; Zhang, Xiquan; Hu, Wenhui European Journal of Medicinal Chemistry, 2011 , vol. 46, # 1 p. 71 - 76

51322-68-0 ~% 18740-38-0

文献：WO2009/53715 A1, ; Page/Page column 81 ; WO 2009/053715 A1

4651-81-4 917-61-3 ~13% 18740-38-0

文献：Venskutonyte, Raminta; Butini, Stefania; Sanna Coccone, Salvatore; Gemma, Sandra; Brindisi, Margherita; Kumar, Vinod; Guarino, Egeria; Maramai, Samuele; Valenti, Salvatore; Amir, Ahmad; Valades, Elena Anton; Frydenvang, Karla; Kastrup, Jette S.; Novellino, Ettore; Campiani, Giuseppe; Pickering, Darryl S. Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4793 - 4805

14080-51-4 57-13-6 ~71% 18740-38-0

文献：Son, Hoon Young; Song, Yang-Heon Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 8 p. 2242 - 2246

4651-81-4 ~% 18740-38-0

文献：Journal of Medicinal Chemistry, , vol. 54, # 22 p. 7815 - 7833

18740-39-1 ~% 18740-38-0

文献：Bulletin de la Societe Chimique de France, , p. 587 - 591

56844-43-0 ~% 18740-38-0

文献：Bulletin de la Societe Chimique de France, , p. 592 - 597

106666-44-8 57-13-6 ~% 18740-38-0

文献：Bulletin de la Societe Chimique de France, , p. 587 - 591

上下游产品

上游产品  8
1189-71-5 4651-81-4 57-13-6 51322-68-0
917-61-3 14080-51-4 18740-39-1 56844-43-0
下游产品  2
18740-39-1 955978-98-0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%