品牌现货直购
供应商:我要出现这里



查看所有供应商和价格请点击:

252882-60-3生产厂家

252882-60-3价格

252882-60-3

252882-60-3结构式
252882-60-3结构式

化源商城直购

中文名 1’-BOC-1,2-二氢-2-氧代-螺[3H-吲哚-3,4’-哌啶]
英文名 tert-butyl 2-oxospiro[1H-indole-3,4'-piperidine]-1'-carboxylate
中文别名 1-Boc-1.2-二氢-2-氧代-螺
1'-BOC-1,2-二氢-2-氧代-螺[3H-吲哚-3,4'-哌啶]
1,2-二氢-2-氧代螺[3H-吲哚-3,4'-哌啶]-1'-羧酸叔丁酯
2-氧代螺吲哚啉-3,4’-哌啶-1’-羧酸叔丁酯
英文别名 tert-Butyl 2-oxo-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxylate
tert-Butyl 2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
2-Methyl-2-propanyl 2-oxo-1,2-dihydro-1'H-spiro[indole-3,4'-piperidine]-1'-carboxylate
Spiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid, 1,2-dihydro-2-oxo-, 1,1-dimethylethyl ester
密度 1.2±0.1 g/cm3
沸点 475.6±45.0 °C at 760 mmHg
分子式 C17H22N2O3
分子量 302.368
闪点 241.4±28.7 °C
精确质量 302.163055
PSA 58.64000
LogP 2.69
蒸汽压 0.0±1.2 mmHg at 25°C
折射率 1.587
储存条件 2-8°C
Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 1’-Boc-1,2-dihydro-2-oxo-spiro[3h-indole-3,4’-piperidine]
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:1’-Boc-1,2-dihydro-2-oxo-spiro[3h-indole-3,4’-piperidine]
CAS number:252882-60-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C17H22N2O3
Molecular weight:302.4

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A
危害码 (欧洲) Xi
海关编码 2933399090

~99%

252882-60-3结构式

252882-60-3

文献:JANSSEN RandD IRELAND; TAHRI, Abdellah; VENDEVILLE, Sandrine Marie Helene; JONCKERS, Tim Hugo Maria; RABOISSON, Pierre Jean-Marie Bernard; HU, Lili; DEMIN, Samuël Dominique; COOYMANS, Ludwig Paul Patent: WO2014/60411 A1, 2014 ; Location in patent: Page/Page column 36; 37 ;

~83%

252882-60-3结构式

252882-60-3

文献:Vachal, Petr; Miao, Shouwu; Pierce, Joan M.; Guiadeen, Deodial; Colandrea, Vincent J.; Wyvratt, Matthew J.; Salowe, Scott P.; Sonatore, Lisa M.; Milligan, James A.; Hajdu, Richard; Gollapudi, Anantha; Keohane, Carol A.; Lingham, Russell B.; Mandala, Suzanne M.; Demartino, Julie A.; Tong, Xinchun; Wolff, Michael; Steinhuebel, Dietrich; Kieczykowski, Gerard R.; Fleitz, Fred J.; Chapman, Kevin; Athanasopoulos, John; Adam, Gregory; Akyuz, Can D.; Jena, Dhirendra K.; Lusen, Jeffrey W.; Meng, Juncai; Stein, Benjamin D.; Xia, Lei; Sherer, Edward C.; Hale, Jeffrey J. Journal of Medicinal Chemistry, 2012 , vol. 55, # 7 p. 2945 - 2959

~%

252882-60-3结构式

252882-60-3

文献:WO2007/28638 A1, ; Page/Page column 96 ; WO 2007/028638 A1

~%

252882-60-3结构式

252882-60-3

文献:WO2009/61676 A2, ; Page/Page column 76-77 ; WO 2009/061676 A2

~%

252882-60-3结构式

252882-60-3

文献:WO2014/60411 A1, ;
海关编码 2933399090
中文概述 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%