92623-83-1

• 常用中文名：普拉朵林
• 常用英文名：Pravadoline
• CAS号：92623-83-1
• 分子式：C₂₃H₂₆N₂O₃
• 分子量：378.464
• 发布时间：2018-07-12 21:00:12
• 更新时间：2025-08-23 10:18:34
• Pravadoline is a cannabimimetic aminoalkylindole agonist of the cannabinoid receptors and an inhibitor of Cox-1 and Cox-2, demonstrating powerful analgesic effects through the combination of these actions.

名称

• 中文名: 普拉朵林
• 英文名: (4-Methoxyphenyl)(2-methyl-1-(2-morpholinoethyl)-1H-indol-3-yl)methanone
• 中文别名: (4-甲氧基苯基)-[2-甲基-1-(2-吗啉-4-乙基)吲哚-3-基]甲酮; (4-甲氧基苯基)(2-甲基-1-(2-吗啉-4-基乙基)-1H-吲哚-3-基)甲酮
• 英文别名: Methanone, (4-methoxyphenyl)[2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]-; (4-Methoxyphenyl){2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl}methanone; (4-Methoxyphenyl){2-methyl-1-[2-(morpholin-4-yl)ethyl]-1H-indol-3-yl}methanone; WIN 48098; p-Methoxyphenyl 2-Methyl-1-(2-morpholinoethyl)indol-3-yl Ketone; (4-Methoxyphenyl)[2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]methanone; Methanone, (4-methoxyphenyl)(2-methyl-1-(2-(4-morpholinyl)ethyl)-1H-indol-3-yl)-; (4-methoxyphenyl)-[2-methyl-1-(2-morpholin-4-ylethyl)indol-3-yl]methanone; Pravadoline

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 553.1±50.0 °C at 760 mmHg
• 分子式: C₂₃H₂₆N₂O₃
• 分子量: 378.464
• 闪点: 288.3±30.1 °C
• 精确质量: 378.194336
• PSA: 43.70000
• LogP: 3.62
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.603
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

26211-90-5 3647-69-6 ~60% 92623-83-1

文献：Gong, Tian-Jun; Cheng, Wan-Min; Su, Wei; Xiao, Bin; Fu, Yao Tetrahedron Letters, 2014 , vol. 55, # 11 p. 1859 - 1862

622-40-2 137641-88-4 ~92% 92623-83-1

文献：Eissenstat, Michael A.; Weaver, John D. Tetrahedron Letters, 1995 , vol. 36, # 12 p. 2029 - 2032

95-20-5 ~% 92623-83-1

文献：Journal of Medicinal Chemistry, , vol. 34, # 3 p. 1099 - 1110

100-07-2 ~% 92623-83-1

文献：Journal of Medicinal Chemistry, , vol. 34, # 3 p. 1099 - 1110

103-84-4 ~% 92623-83-1

文献：Tetrahedron Letters, , vol. 55, # 11 p. 1859 - 1862

169214-12-4 ~% 92623-83-1

文献：Tetrahedron Letters, , vol. 55, # 11 p. 1859 - 1862

37842-85-6 ~% 92623-83-1

文献：Tetrahedron Letters, , vol. 55, # 11 p. 1859 - 1862

68267-69-6 ~% 92623-83-1

文献：Tetrahedron Letters, , vol. 55, # 11 p. 1859 - 1862

95-20-5 100-07-2 ~% 92623-83-1

文献：Tetrahedron Letters, , vol. 55, # 11 p. 1859 - 1862

上下游产品

上游产品  9
26211-90-5 3647-69-6 622-40-2 137641-88-4
95-20-5 100-07-2 103-84-4 169214-12-4
37842-85-6
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%