39277-41-3

• 常用中文名：弧菌毒素
• 常用英文名：Viridicatumtoxin
• CAS号：39277-41-3
• 分子式：C₃₀H₃₁NO₁₀
• 分子量：565.56800
• 相关类别： 研究领域 感染
• 发布时间：2017-04-10 11:48:29
• 更新时间：2024-01-09 10:40:47
• 青霉毒素是从青霉中提取的一种新型真菌毒素,在大鼠体内的LD50为122.4 mg/kg。

名称

• 中文名: 弧菌毒素
• 英文名: viridicatumtoxin
• 英文别名: Virginiamycin butanolide D; virginiae butanolide D; (8,8'-Bi-1H-naphtho[2,3-c]pyran)-3,3'-diacetic acid, 3,3',4,4'-tetrahydro-9,9',10,10'-tetrahydroxy-7,7'-dimethoxy-1,1'-dioxo-, dimethyl ester

物化性质

• 密度: 1.64g/cm3
• 沸点: 711.8ºC at 760mmHg
• 分子式: C₃₀H₃₁NO₁₀
• 分子量: 565.56800
• 闪点: 384.3ºC
• 精确质量: 565.19500
• PSA: 207.84000
• LogP: 2.48220
• 折射率: 1.771

生物活性

• 描述: 青霉毒素是从青霉中提取的一种新型真菌毒素,在大鼠体内的LD50为122.4 mg/kg。
• 相关类别:
  研究领域 >> 感染
• 参考文献:

  [1]. Hutchison RD, et al. Viridicatumtoxin, a new mycotoxin from Penicillium viridicatum Westling. Toxicol Appl Pharmacol. 1973;24(3):507-509.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : ZA4930000 CHEMICAL NAME : Viridicatumtoxin CAS REGISTRY NUMBER : 39277-41-3 LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C30-H31-N-O10 MOLECULAR WEIGHT : 565.62 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 122 mg/kg TOXIC EFFECTS : Cardiac - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in spleen TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Gastrointestinal - peritonitis Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - dehydration TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Gastrointestinal - peritonitis Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - dehydration MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 25 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,193,1978