210101-16-9

• 常用中文名：考尼伐坦
• 常用英文名：Conivaptan
• CAS号：210101-16-9
• 分子式：C₃₂H₂₆N₄O₂
• 分子量：498.574
• 发布时间：2018-07-14 16:22:02
• 更新时间：2024-01-13 17:29:30
• A potent, selective, nonpeptide vasopressin V1A and V2 receptor antagonist with Ki of 0.48 nM and 3.04 nM respectively.

名称

• 中文名: 考尼伐坦
• 英文名: conivaptan
• 英文别名: [1,1'-biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(3H)-yl)carbonyl]phenyl]-; [1,1'-Biphenyl]-2-carboxamide, N-[4-[(4,5-dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-; YM087; Conivaptan (INN); N-{4-[(2-Methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(3H)-yl)carbonyl]phenyl}biphenyl-2-carboxamide; UNII-0NJ98Y462X; Conivaptan; N-{4-[(2-Methyl-4,5-dihydroimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl}-2-biphenylcarboxamide; N-[4-(2-methyl-4,5-dihydro-3H-imidazo[4,5-d][1]benzazepine-6-carbonyl)phenyl]-2-phenylbenzamide

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 751.2±60.0 °C at 760 mmHg
• 分子式: C₃₂H₂₆N₄O₂
• 分子量: 498.574
• 闪点: 408.1±32.9 °C
• 精确质量: 498.205566
• PSA: 78.09000
• LogP: 4.40
• 蒸汽压: 0.0±2.5 mmHg at 25°C
• 折射率: 1.699