185099-68-7

• 常用中文名：8-Boc-3-(三氟甲基磺酰氧基)-8-氮杂双环[3.2.1]辛-3-烯
• 常用英文名：8-BOC-3-(TRIFLUOROMETHYLSULFONYLOXY)-8-AZABICYCLO[3.2.1]OCT-3-ENE
• CAS号：185099-68-7
• 分子式：C₁₃H₁₈F₃NO₅S
• 分子量：357.346
• 发布时间：2018-12-28 11:04:37
• 更新时间：2024-01-19 17:50:50

名称

• 中文名: (1R,5S)-3-(三氟甲基磺酰氧基)-8-氮杂双环[3.2.1]-2-辛烯-8-羧酸叔丁酯
• 英文名: tert-butyl 3-(trifluoromethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene-8-carboxylate
• 英文别名: tert-Butyl 3-{[(trifluoromethyl)sulfonyl]oxy}-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylate; tert-Butyl 3-(trifluoromethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene-8-carboxylate; 8-Boc-3-(trifluoromethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-3-ene; 2-Methyl-2-propanyl 3-{[(trifluoromethyl)sulfonyl]oxy}-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylate; 8-Azabicyclo[3.2.1]oct-2-ene-8-carboxylic acid, 3-[[(trifluoromethyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester; (1R,5S)-tert-Butyl 3-(trifluoromethylsulfonyloxy)-8-azabicyclo[3.2.1]oct-2-ene-8-carboxylate

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 392.9±42.0 °C at 760 mmHg
• 分子式: C₁₃H₁₈F₃NO₅S
• 分子量: 357.346
• 闪点: 191.4±27.9 °C
• 精确质量: 357.085785
• PSA: 81.29000
• LogP: 3.40
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.504
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

37595-74-7 185099-67-6 ~92% 185099-68-7

文献：Lu, Zhijian; Tata, James R.; Cheng, Kang; Wei, Liente; Chan, Wanda W.-S.; Butler, Bridget; Schleim, Klaus D.; Jacks, Thomas M.; Hickey, Gerard; Patchett, Arthur A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1817 - 1820

145100-51-2 185099-67-6 ~91% 185099-68-7

文献：Purandare, Ashok Vinayak; Wan, Honghe; Huynh, Tram N. Patent: US2006/235037 A1, 2006 ; Location in patent: Page/Page column 59 ; US 20060235037 A1

185099-67-6 ~80% 185099-68-7

文献：Liang, Guyan; Choi-Sledeski, Yong Mi; Shum, Patrick; Chen, Xin; Poli, Gregory B.; Kumar, Vasant; Minnich, Anne; Wang, Qingping; Tsay, Joseph; Sides, Keith; Kang, Jiesheng; Zhang, Ying Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1606 - 1610

24424-99-5 ~% 185099-68-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 10 p. 1817 - 1820

532-24-1 ~% 185099-68-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 10 p. 1817 - 1820

25602-68-0 ~% 185099-68-7

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 10 p. 1817 - 1820

上下游产品

上游产品  6
37595-74-7 185099-67-6 145100-51-2 24424-99-5
532-24-1 25602-68-0
下游产品  2
900503-08-4 1204809-89-1

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%