122194-07-4

• 常用中文名：N,N-二异丙基亚磷酰胺二甲基
• 常用英文名：dimethyl n,n-diisopropylphosphoramidite
• CAS号：122194-07-4
• 分子式：C₈H₂₀NO₂P
• 分子量：193.22400
• 发布时间：2018-11-28 19:11:28
• 更新时间：2025-08-31 16:44:16
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名称

• 中文名: N,N-二异丙基亚膦酸二甲酯酰胺
• 英文名: dimethyl n,n-diisopropylphosphoramidite
• 英文别名: DIMETHYL N N-DIISOPROPYLPHOSPHORAMIDITE; N,N-diisopropyl-dimethylphosphoramidite; (DIMETHOXYPHOSPHANYL)BIS(PROPAN-2-YL)AMINE; (dimethoxyphosphanyl)diisopropylamine; dimethoxy-N,N-diisopropylphosphoramidite; DIMETHYL-N,N-DIISOPROPYLPHOSPHORAMIDITE; DIMETHYL-N,N-DIISOPROPYLPHOSPHOROAMIDITE; dimethyl-N,N-diisopropylphosphoramidite; O,O-dimethyl-N,N-diisopropylphosphoramidite

物化性质

• 密度: 0.840 g/mL at 20ºC(lit.)
• 沸点: 54ºC10 mm Hg(lit.)
• 分子式: C₈H₂₀NO₂P
• 分子量: 193.22400
• 闪点: 100ºC
• 精确质量: 193.12300
• PSA: 35.29000
• LogP: 2.62490
• 折射率: n20/D 1.420(lit.)
• 储存条件: -20°C，保存于惰性气体中

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 个人防护装备: Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26
• 危险品运输编码: NONH for all modes of transport

合成路线

124-41-4 86030-43-5 ~90% 122194-07-4

文献：Dias; Mornet; Kotoujansky Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 1 p. 73 - 78

67-56-1 56183-63-2 ~% 122194-07-4

文献：Shukla, Deepak; Lu, Cuong; Schepp, Norman P.; Bentrude, Wesley G.; Johnston, Linda J. Journal of Organic Chemistry, 2000 , vol. 65, # 19 p. 6167 - 6172

67-56-1 921-26-6 ~48% 122194-07-4

文献：Nurminen, Erkki J.; Mattinen, Jorma K.; Loennberg, Harri Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 7 p. 1621 - 1628

67-56-1 92611-10-4 ~% 122194-07-4

文献：McBride, Lincoln J.; Kierzek, Ryszard; Beaucage, Serge L.; Caruthers, Marvin H. Journal of the American Chemical Society, 1986 , vol. 108, # 8 p. 2040 - 2048

108-18-9 ~% 122194-07-4

文献：Nurminen, Erkki J.; Mattinen, Jorma K.; Loennberg, Harri Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 7 p. 1621 - 1628

67-56-1 96163-52-9 ~% 122194-07-4

文献：Wada; Ishikawa; Hata Tetrahedron Letters, 1990 , vol. 31, # 44 p. 6363 - 6366