328073-92-3

• 常用中文名：VEGF Inducer, GS4012
• 常用英文名：VEGF Inducer, GS4012
• CAS号：328073-92-3
• 分子式：C₁₄H₁₅NOSHCl
• 分子量：281.8
• 发布时间：2022-05-06 21:20:27
• 更新时间：2024-01-11 10:23:49
• VEGF诱导剂GS4012是细胞可渗透的吡啶基-硫醚化合物，可作为VEGF和VEGF介导的血管形成的有效诱导剂。GS4012诱导的VEGF上调与其抑制斑马鱼的僵锁/缩窄表型（7.5μg/ ml）以及刺激HUVEC中的肾小管网络形成（5μg/ ml）密切相关。 VEGF Inducer, GS4012 is a cell-permeable pyridinyl-thioether compound which acts as a potent inducer of VEGF and VEGF-mediated vessel formation. GS4012-induced upregulation of VEGF correlates well with its ability to suppress the gridlock/coarctation phenotype (7.5 μg/ml) in Zebrafish as well as to stimulate tubule network formation (5 μg/ml) in HUVECs.

名称

• 英文名: VEGF Inducer, GS4012
• 英文别名: 4-(2-(4-Methoxyphenylsulfanyl)ethyl)pyridine HCl; Pyridine, 4-[2-[(4-methoxyphenyl)thio]ethyl]-, hydrochloride (1:1); GS4012; 4-{2-[(4-Methoxyphenyl)sulfanyl]ethyl}pyridine hydrochloride (1:1)

物化性质

• 沸点: 431.9° C at 760 mmHg (Predicted)
• 分子式: C₁₄H₁₅NOSHCl
• 分子量: 281.8
• 精确质量: 281.064117
• 储存条件: 2-8°C储存
• 水溶解性: Soluble in DMSO (200 mg/ml), methanol (50 mg/ml), and water.