2172819-74-6

• 常用中文名：VH 032 酰胺-烷基C4-酸
• 常用英文名：VH032-linker 5
• CAS号：2172819-74-6
• 分子式：C₂₈H₃₈N₄O₆S
• 分子量：558.690
• 发布时间：2021-01-09 10:50:10
• 更新时间：2024-04-08 22:24:12
• VH032-linker 5 is a derivative of the proteolysis-targeting chimera technology (PROTAC) for PROTAC research and development; by incorporating an E3 ligase ligand and an alkyl C4 linker with terminal carboxylic acid, it is ready for conjugation to a target protein ligand.

名称

• 中文名: VH 032 酰胺-烷基C4-酸
• 英文名: N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
• 英文别名: L-Prolinamide, N-(5-carboxy-1-oxopentyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-; N-(5-Carboxypentanoyl)-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 878.5±65.0 °C at 760 mmHg
• 分子式: C₂₈H₃₈N₄O₆S
• 分子量: 558.690
• 闪点: 485.1±34.3 °C
• 精确质量: 558.251221
• LogP: 1.17
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.586