1398053-45-6

• 常用中文名：CC 122 HCl
• 常用英文名：CC 122 HCl
• CAS号：1398053-45-6
• 分子式：C₁₄H₁₅ClN₄O₃
• 分子量：322.747
• 发布时间：2021-01-01 02:17:37
• 更新时间：2024-01-18 19:55:00
• Avadomide, also known as CC-122, is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes degradation of Aiolos and Ikaros in diffuse large B-cell lymphoma (DLBCL) and T cells in vitro, in vivo, and in patients, resulting in both cell autonomous as well as immunostimulatory effects.

名称

• 英文名: Avadomide hydrochloride
• 英文别名: 3-(5-Amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-2,6-piperidinedione hydrochloride (1:1); Avadomide hydrochloride; 2,6-Piperidinedione, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-, hydrochloride (1:1); CC-122 HCl; UNII:28DZS29F59

物化性质

• 分子式: C₁₄H₁₅ClN₄O₃
• 分子量: 322.747
• 精确质量: 322.083282