76-84-6

• 常用中文名：三苯基甲醇
• 常用英文名：Tritanol
• CAS号：76-84-6
• 分子式：C₁₉H₁₆O
• 分子量：260.330
• 相关类别： 化学试剂 有机试剂 芳香醇
• 发布时间：2018-07-24 20:08:53
• 更新时间：2024-01-02 10:09:07
• 【用途一】
  用于有机合成
  【用途二】
  有机合成中间体。

名称

• 中文名: 三苯基甲醇
• 英文名: Triphenylmethanol
• 中文别名: 羟基三苯基甲烷; 三苯甲醇; 氯沙坦钾杂质 G
• 英文别名: Benzenemethanol, α,α-diphenyl-; TRIPHENYLCARBINOL; Ih-Tetrazole; PH3C-OH; Methanol, triphenyl- (8CI); Triphenylmethanol; Methanol, triphenyl-; Tritylcarbinol; EINECS 200-988-5; TRT-OH; α,α-Diphenyl-benzylalcohol; diphenyl-phenyl carbinol; triphenyl methanol; Tritanol; trityl alcohol; Triphenylmethyl alcohol; triphenylcarbinole; BL 3756; MFCD00004445

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 380.0±0.0 °C at 760 mmHg
• 熔点: 160-163 °C(lit.)
• 分子式: C₁₉H₁₆O
• 分子量: 260.330
• 闪点: 168.7±15.9 °C
• 精确质量: 260.120117
• PSA: 20.23000
• LogP: 4.59
• 外观性状: 白色至灰白色粉末
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.622
• 储存条件:

  阴凉处密封保存。

• 稳定性: Stable. Combustible. Incompatible with oxidizing agents, acids, acid chlorides, acid anhydrides.
• 水溶解性: INSOLUBLE
• 分子结构:

  1、 摩尔折射率：81.07

  2、 摩尔体积（m³/mol）：230.2

  3、 等张比容（90.2K）：601.1

  4、 表面张力（dyne/cm）：46.4

  5、 极化率（10 ^-24cm ³）：32.13

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:1

  4.可旋转化学键数量:3

  5.互变异构体数量:无

  6.拓扑分子极性表面积20.2

  7.重原子数量:20

  8.表面电荷:0

  9.复杂度:235

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：片状晶体。

  2. 密度（g/mL,25/4℃）：1.199

  3. 相对蒸汽密度（g/mL,空气=1）：不确定

  4. 熔点（ºC）：164.2℃

  5. 沸点（ºC,常压）：380℃

  6. 沸点（ºC,5.2kPa）：不确定

  7. 折射率：1.4896（25℃）

  8. 闪点（ºC）：不确定

  9. 比旋光度（º）：-14.7°(c=2.5，氯仿)

  10. 自燃点或引燃温度（ºC）：不确定

  11. 蒸气压（kPa,25ºC）：不确定

  12. 饱和蒸气压（kPa,60ºC）：不确定

  13. 燃烧热（KJ/mol）：不确定

  14. 临界温度（ºC）：不确定

  15. 临界压力（KPa）：不确定

  16. 油水（辛醇/水）分配系数的对数值：不确定

  17. 爆炸上限（%,V/V）：不确定

  18. 爆炸下限（%,V/V）：不确定

  19. 溶解性：不溶于水和石油醚，溶于乙醇、乙醚、丙酮、苯，溶于浓硫酸显黄色，溶于冰乙酸时无色

MSDS

Name: Triphenylmethanol 97% Material Safety Data Sheet Synonym: Triphenylcarbinol; Trityl alcoho CAS: 76-84-6 Section 1 - Chemical Product MSDS Name:Triphenylmethanol 97% Material Safety Data Sheet Synonym:Triphenylcarbinol; Trityl alcoho Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 76-84-6 Triphenylmethanol 97.0 200-988-5 Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: None Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Remove from exposure and move to fresh air immediately. Get medical aid if cough or other symptoms appear. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 76-84-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: beige Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 380 deg C @ 760.00mmHg Freezing/Melting Point: 164.2 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: insoluble Specific Gravity/Density: 1.199 Molecular Formula: C19H16O Molecular Weight: 260.32 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants. Incompatibilities with Other Materials: Acids - acid chlorides - acid anhydrides - oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 76-84-6 unlisted. LD50/LC50: Not available. Carcinogenicity: Triphenylmethanol - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 76-84-6: 2 Canada CAS# 76-84-6 is listed on Canada's DSL List. CAS# 76-84-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 76-84-6 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R38
• 安全声明 (欧洲): S22-S24/25
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3
• 海关编码: 29062900

合成路线

上下游产品

上游产品  10
50653-07-1 519-73-3 595-91-5 108-86-1
119-61-9 876063-01-3 144690-92-6 591-51-5
4510-12-7 100-39-0
下游产品  10
105589-77-3 109545-74-6 105309-59-9 341-02-6
55135-66-5 150025-01-7 146462-60-4 1420-06-0
3695-77-0 20799-66-0

制备

由三苯氯甲烷水解，或溴化苯基镁（格利雅试剂）与二苯甲酮（或苯甲酸乙酯）制备。

海关

海关编码	29062900