34597-40-5

• 常用中文名：非诺洛芬钙
• 常用英文名：Fenoprofen Calcium
• CAS号：34597-40-5
• 分子式：C₁₅H₁₄Ca_0.5O₃
• 分子量：262.31
• 相关类别： 研究领域 炎症/免疫
• 发布时间：2018-02-21 08:00:00
• 更新时间：2025-08-25 13:39:41
• Fenoprofen钙是非甾体类,抗炎化合物,对关节炎有效。

名称

• 中文名: 非诺洛芬钙
• 英文名: fenoprofen calcium (anhydrous)
• 中文别名: 菲诺洛芬钙
• 英文别名: calciumfenoprofen; FENOPROFEN CALCIUM; Fepron; nalfon; calcium methyl-3-phenoxybenzeneacetate; fenoprofen-calcium dihydrate

物化性质

• 密度: 1.183g/cm3
• 沸点: 381.3ºC at 760mmHg
• 分子式: C₁₅H₁₄Ca_0.5O₃
• 分子量: 262.31
• 闪点: 141.7ºC
• PSA: 71.06000
• LogP: 7.17980
• 外观性状: 粉末
• 储存条件: -20℃

生物活性

• 描述: Fenoprofen钙是非甾体类,抗炎化合物,对关节炎有效。
• 相关类别:
  研究领域 >> 炎症/免疫
• 靶点:

  COX

• 参考文献:

  [1]. Takashima-Hirano M, et al. General method for the (11)C-labeling of 2-arylpropionic acids and their esters: construction of a PET tracer library for a study of biological events involved in COXs expression. Chemistry. 2010 Apr 12;16(14):4250-8.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CY1678870 CHEMICAL NAME : Benzeneacetic acid, alpha-methyl-3-phenoxy-, calcium salt, (+-)- CAS REGISTRY NUMBER : 34597-40-5 LAST UPDATED : 199203 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C30-H26-O6.Ca MOLECULAR WEIGHT : 522.64 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 415 mg/kg TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 14,4385,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 686 mg/kg TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression Blood - changes in spleen REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 14,4385,1980

安全

• 危害码 (欧洲): N