1717-00-6

• 常用中文名：一氟二氯乙烷
• 常用英文名：1,1-Dichloro-1-fluoroethane
• CAS号：1717-00-6
• 分子式：C₂H₃Cl₂F
• 分子量：116.950
• 发布时间：2018-02-08 08:00:00
• 更新时间：2024-01-02 19:21:37
• 【用途一】
  用作清洗剂、聚氨酯发泡剂
  【用途二】
  该产品可替代CFC-11作硬质聚氨酯泡沫塑料的发泡剂，替代CFC-113作清洗剂。

名称

• 中文名: 1-氟-1,1-二氯乙烷
• 英文名: Dichlorofluoroethane
• 中文别名: 1,1-二氯-1-氟乙烷; 1,1-二氯氟乙烷; 一氟二氯乙烷; 氟里昂-141b; 1,1-二氯氟乙烷
• 英文别名: CFC 141b; R 141b; 1,1-dichlorofluoroethane; F141b; HCFC 141b; Ethane, dichlorofluoro-; 1,1-Dichloro-1-fluoroethane; Refrigerant 141b; HFA-141B; HCFC-141b; HFC141B; dichloro-1-fluoroethane; MFCD00042461; 1-fluoro 1,1-dichloroethane; EINECS 404-080-1; 1,1-Chloro-1-fluoroethane; Ethane, 1,1-dichloro-1-fluoro-; monofluorodichloroethane; GXGF1; DF-141b; Isotron 141b; cfc141b; Freon 141b; Solkane 141b; dichloromonofluoroethane; FC-141B

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 35.5±8.0 °C at 760 mmHg
• 熔点: -104ºC
• 分子式: C₂H₃Cl₂F
• 分子量: 116.950
• 闪点: -33.4±11.9 °C
• 精确质量: 115.959587
• LogP: 1.75
• 外观性状: 无色液体弱像空气的气味
• 蒸汽压: 521.9±0.1 mmHg at 25°C
• 折射率: 1.387
• 稳定性: Stable.
• 计算化学:

  1.疏水参数计算参考值（XlogP）:2.2

  2.氢键供体数量:0

  3.氢键受体数量:1

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积:0

  7.重原子数量:5

  8.表面电荷:0

  9.复杂度:34.6

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KI0997000 CHEMICAL NAME : Ethane, 1,1-dichloro-1-fluoro- CAS REGISTRY NUMBER : 1717-00-6 BEILSTEIN REFERENCE NO. : 1731585 LAST UPDATED : 199806 DATA ITEMS CITED : 16 MOLECULAR FORMULA : C2-H3-Cl2-F MOLECULAR WEIGHT : 116.95 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 56700 ppm/6H TOXIC EFFECTS : Behavioral - tremor Behavioral - ataxia TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Liver - other changes TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 151 gm/m3/2H TOXIC EFFECTS : Behavioral - general anesthetic Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 50 gm/m3/4H/4W-I TOXIC EFFECTS : Endocrine - evidence of thyroid hypofunction TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 18200 mg/m3/4H/26W-I TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section Kidney, Ureter, Bladder - proteinuria Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20000 ppm/6H/28D-I TOXIC EFFECTS : Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 18200 mg/m3/4H/26W-I TOXIC EFFECTS : Blood - changes in leukocyte (WBC) count TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 20000 ppm/6H SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 20000 ppm/6H SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death MUTATION DATA TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 10 pph/4H (Continuous) REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 33,491,1995

安全

• 危害码 (欧洲): Xi: Irritant;N: Dangerous for the environment;
• 风险声明 (欧洲): R59
• 安全声明 (欧洲): 23-36/37/39-61-59
• 危险品运输编码: UN 9274
• 海关编码: 2903730000

合成路线

上下游产品

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75-35-4 7783-71-3 71-55-6 76-13-1
7664-39-3 7783-56-4 75-09-2 79-51-6
67-64-1 7647-18-9
下游产品  10
420-46-2 75-68-3 2317-91-1 75-35-4
64-19-7 353-36-6 75-00-3 1615-75-4
1649-08-7 60048-13-7

海关

海关编码	2903791014
中文概述	2903791014 1-氟-1,1-二氯乙烷。监管条件:14xy。增值税率:17.0%。退税率:9.0%。最低关税:5.5%。普通关税:30.0%
Summary	2903791014 1,1-dichloro-1-fluoroethane。supervision conditions:14xy。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%