373603-69-1

• 常用中文名：4-(三氟甲基)哌啶-4-醇
• 常用英文名：4-(TRIFLUOROMETHYL)PIPERIDIN-4-OL
• CAS号：373603-69-1
• 分子式：C₆H₁₀F₃NO
• 分子量：169.14500
• 发布时间：2018-06-08 14:23:50
• 更新时间：2025-09-18 10:15:54

名称

• 中文名: 4-(三氟甲基)哌啶-4-醇
• 英文名: 4-(Trifluoromethyl)-4-piperidinol
• 英文别名: 4-trifluoromethylpiperidin-4-ol; 4-hydroxy-4-tert-butoxycarbonylaminomethylpiperidine; 4-hydroxy-4-trifluoromethyl-piperdine; 4-hydroxy-4-trifluoromethyl-piperidine

物化性质

• 沸点: 175.1±35.0 °C at 760 mmHg
• 分子式: C₆H₁₀F₃NO
• 分子量: 169.14500
• 精确质量: 169.07100
• PSA: 32.26000
• LogP: 0.99200
• 外观性状: 淡黄色至黄褐色固体
• 储存条件: 2-8°C，密封，干燥

安全

• 危害码 (欧洲): Xn

合成路线

373603-70-4 ~99% 373603-69-1

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2005/103002 A2, 2005 ; Location in patent: Page/Page column 34 ; WO 2005/103002 A2

946504-83-2 ~97% 373603-69-1

文献：Hendricks, Robert Than; Hermann, Johannes; Kondru, Rama; Lou, Yan; Lynch, Stephen M.; Owens, Timothy D.; Soth, Michael Patent: US2011/230462 A1, 2011 ; Location in patent: Page/Page column 81 ; US 20110230462 A1

550371-74-9 ~99% 373603-69-1

文献：EXELIXIS, INC.; AAY, Naing; ARCALAS, Arlyn; BOWLES, Owen, Joseph; BUSSENIUS, Joerg; CURTIS, Jeffry, Kimo; DEFINA, Steven, Charles; DUBENKO, Larisa; HARRIS, Jason, R.; JACKSON-UGUETO, Eileen, E.; MANALO, Jean-Claire, Limun; KIM, Angie, Inyoung; PACK, Michael; PETO, Csaba, J.; RICE, Kenneth, D.; TSANG, Tsze, H. Patent: WO2010/138487 A1, 2010 ; Location in patent: Page/Page column 130 ; WO 2010/138487 A1

550371-74-9 76-05-1 ~99% 373603-69-1

文献：EXELIXIS, INC.; RICE, Kenneth Patent: WO2012/71509 A2, 2012 ; Location in patent: Page/Page column 165 ; WO 2012/071509 A2

19099-93-5 ~% 373603-69-1

文献：Hendricks, Robert Than; Hermann, Johannes; Kondru, Rama; Lou, Yan; Lynch, Stephen M.; Owens, Timothy D.; Soth, Michael Patent: US2011/230462 A1, 2011 ; US 20110230462 A1

79099-07-3 ~% 373603-69-1

文献：EXELIXIS, INC.; RICE, Kenneth Patent: WO2012/71509 A2, 2012 ; WO 2012/071509 A2

上下游产品

上游产品  4
550371-74-9 76-05-1 19099-93-5 79099-07-3
下游产品  0