168162-30-9

• 常用中文名：3-(叔丁氧基羰基)苯甲酸
• 常用英文名：3-(tert-Butoxycarbonyl)benzoic acid
• CAS号：168162-30-9
• 分子式：C₁₃H₁₇NO₄
• 分子量：222.237
• 发布时间：2018-02-10 08:00:00
• 更新时间：2025-08-25 14:11:27

名称

• 中文名: 3-(叔丁氧基羰基)苯甲酸
• 英文名: 3-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]benzoic acid
• 英文别名: 3-{[(2-Methyl-2-propanyl)oxy]carbonyl}benzoic acid; 3-[N-(tert-butyloxycarbonyl)methylamino]benzoic acid; 3-(tert-Butoxycarbonyl)benzoic acid; 3-(N-Boc-N-methylamino)benzoic acid; 3-(tert-butoxycarbonylaminomethyl)benzoic acid; 3-(N-tert-butoxylcarbonyl-N-methylamino)benzoic acid; 3-(N-tert-butoxycarbonyl-N-methyl)aminobenzoic acid; 1,3-Benzenedicarboxylic acid, mono(1,1-dimethylethyl) ester

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 357.6±25.0 °C at 760 mmHg
• 分子式: C₁₃H₁₇NO₄
• 分子量: 222.237
• 闪点: 135.5±16.7 °C
• 精确质量: 222.089203
• PSA: 66.84000
• LogP: 3.06
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.533

合成路线

111331-82-9 ~79% 168162-30-9

文献：Ferring-Research Limited; Yamanouchi Pharmaceutical Co. Ltd. Patent: US5728829 A1, 1998 ;

168162-31-0 ~% 168162-30-9

文献：Japan Tobacco Inc. Patent: US2006/35939 A1, 2006 ; Location in patent: Page/Page column 19 ;

24424-99-5 ~% 168162-30-9

文献：Semple, Graeme; Ryder, Hamish; Rooker, David P.; Batt, Andrzej R.; Kendrick, David A.; Szelke, Michael; Ohta, Mitsuaki; Satoh, Masato; Nishida, Akito; Akuzawa, Shinobu; Miyata, Keiji Journal of Medicinal Chemistry, 1997 , vol. 40, # 3 p. 331 - 341

99-05-8 ~% 168162-30-9

文献：Semple, Graeme; Ryder, Hamish; Rooker, David P.; Batt, Andrzej R.; Kendrick, David A.; Szelke, Michael; Ohta, Mitsuaki; Satoh, Masato; Nishida, Akito; Akuzawa, Shinobu; Miyata, Keiji Journal of Medicinal Chemistry, 1997 , vol. 40, # 3 p. 331 - 341

24424-99-5 51524-84-6 ~% 168162-30-9

文献：Deberardinis, Albert M.; Banerjee, Upasana; Hadden, M. Kyle ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 7 p. 590 - 595

111331-82-9 74-88-4 ~% 168162-30-9

文献：Semple, Graeme; Ryder, Hamish; Rooker, David P.; Batt, Andrzej R.; Kendrick, David A.; Szelke, Michael; Ohta, Mitsuaki; Satoh, Masato; Nishida, Akito; Akuzawa, Shinobu; Miyata, Keiji Journal of Medicinal Chemistry, 1997 , vol. 40, # 3 p. 331 - 341