768350-54-5

• 常用中文名：7-(苄氧基)-4-(4-溴-2-氟苯胺基)-6-甲氧基喹唑啉
• 常用英文名：7-(benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
• CAS号：768350-54-5
• 分子式：C₂₂H₁₇BrFN₃O₂
• 分子量：454.29200
• 相关类别： 有机原料 有机氟化合物 氟苯胺系列
• 发布时间：2019-01-17 21:49:07
• 更新时间：2024-01-11 09:23:32

名称

• 中文名: 7-(苄氧基)-N-(4-溴-2-氟苯基)-6-甲氧基喹唑啉-4-胺
• 英文名: N-(4-bromo-2-fluorophenyl)-6-methoxy-7-phenylmethoxyquinazolin-4-amine
• 英文别名: qc-1061

物化性质

• 密度: 1.489 g/cm3
• 沸点: 541.094ºC at 760 mmHg
• 分子式: C₂₂H₁₇BrFN₃O₂
• 分子量: 454.29200
• 闪点: 281.044ºC
• 精确质量: 453.04900
• PSA: 56.27000
• LogP: 5.93560
• 储存条件: 室温，避光，保存于惰性气体中

安全

• 海关编码: 2933990090

合成路线

367-24-8 162364-72-9 ~93% 768350-54-5

文献：Gao, Mingzhang; Lola, Christian M.; Wang, Min; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3222 - 3226

60547-98-0 ~% 768350-54-5

文献：Hennequin, Laurent F.; Thomas, Andrew P.; Johnstone, Craig; Stokes, Elaine S. E.; Ple, Patrick A.; Lohmann, Jean-Jacques M.; Ogilvie, Donald J.; Dukes, Mike; Wedge, Steve R.; Curwen, Jon O.; Kendrew, Jane; Lambert-Van Der Brempt, Christine Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5369 - 5389

179688-01-8 ~% 768350-54-5

文献：Hennequin, Laurent F.; Thomas, Andrew P.; Johnstone, Craig; Stokes, Elaine S. E.; Ple, Patrick A.; Lohmann, Jean-Jacques M.; Ogilvie, Donald J.; Dukes, Mike; Wedge, Steve R.; Curwen, Jon O.; Kendrew, Jane; Lambert-Van Der Brempt, Christine Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5369 - 5389

60547-92-4 ~% 768350-54-5

文献：HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup Patent: WO2012/30160 A2, 2012 ;

2426-84-8 ~% 768350-54-5

文献：HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup Patent: WO2012/30160 A2, 2012 ;

60547-94-6 ~% 768350-54-5

文献：HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup Patent: WO2012/30160 A2, 2012 ;

2426-87-1 ~% 768350-54-5

文献：HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup Patent: WO2012/30160 A2, 2012 ;

上下游产品

上游产品  8
367-24-8 162364-72-9 60547-98-0 179688-01-8
60547-92-4 2426-84-8 60547-94-6 2426-87-1
下游产品  4
443913-73-3 338992-20-4 338992-12-4 196603-96-0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%