14675-48-0

14675-48-0结构式

常用中文名：(2R,3s,4r,5r)-2-(羟基甲基)-5-(6-甲基-9h-嘌呤-9-基)四氢呋喃-3,4-二醇
常用英文名：9H-Purine, 6-methyl-9-b-D-ribofuranosyl
CAS号：14675-48-0
分子式：C₁₁H₁₄N₄O₄
分子量：266.25
相关类别：信号通路细胞周期/DNA损伤核苷抗代谢药/类似物
发布时间：2018-12-29 18:05:33
更新时间：2026-08-15 07:47:42
6-甲基嘌呤核苷是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。

中文名	(2R,3s,4r,5r)-2-(羟基甲基)-5-(6-甲基-9h-嘌呤-9-基)四氢呋喃-3,4-二醇
英文名	6-methylpurine riboside
中文别名	6-甲基-9-BETA-D-呋喃核糖基嘌呤 6-甲基嘌呤-BETA-D-核糖苷 6-甲基嘌呤核糖 (2R,3S,4R,5R)-2-(羟基甲基)-5-(6-甲基-9H-嘌呤-9-基)四氢呋喃-3,4-二醇 6-甲基嘌呤核糖苷
英文别名	6-D-MPR (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol 6-Methyl-9-(beta-D-ribofuranosyl)-9H-purine 6-Methylpurine-β-D-riboside 6-Methylpurine ribonucleoside Nsc101619 6-Methylpurine-beta-D-riboside 6-methylpurine-riboside (2r,3s,4r,5r)-2-(hydroxymethyl)-5-(6-methyl-1H-purin-9-yl)tetrahydrofuran-3,4-diol 6-Methyl-9-(1-β-D-ribofuranosyl)purine 6-Methyl-9-(beta-D-ribofuranosyl)-9H-purine, natural antibiotics, antifungal antiviral agent 6-METHYLPURINE RIBOSIDE 6-methyl-9-β-D-ribofuranosyl-9H-purine 9H-Purine, 6-methyl-9-.beta.-D-ribofuranosyl (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolane-3,4-diol 9H-Purine, 6-methyl-9-β-D-ribofuranosyl 6-Methyl-9.beta.-D-ribofuranosylpurine 6-Methylpurine-9-beta-D-ribofuranoside (2R,3S,4R,5R)-2-(HydroxyMethyl)-5-(6-Methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol 6-METHYLPURINE

描述	6-甲基嘌呤核苷是嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性,靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制DNA合成、诱导细胞凋亡等[1]。
相关类别	信号通路 >> 细胞周期/DNA损伤 >> 核苷抗代谢药/类似物研究领域 >> 其他
参考文献	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.