9H-Purine, 6-methyl-9-b-D-ribofuranosyl-

Modify Date: 2024-01-10 20:42:02

9H-Purine, 6-methyl-9-b-D-ribofuranosyl- Structure
9H-Purine, 6-methyl-9-b-D-ribofuranosyl- structure
Common Name 9H-Purine, 6-methyl-9-b-D-ribofuranosyl-
CAS Number 14675-48-0 Molecular Weight 266.25
Density 1.81 g/cm3 Boiling Point 590.4ºC
Molecular Formula C11H14N4O4 Melting Point N/A
MSDS N/A Flash Point 310.9ºC

 Use of 9H-Purine, 6-methyl-9-b-D-ribofuranosyl-


6-Methylpurine riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 6-methylpurine riboside
Synonym More Synonyms

 9H-Purine, 6-methyl-9-b-D-ribofuranosyl- Biological Activity

Description 6-Methylpurine riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.81 g/cm3
Boiling Point 590.4ºC
Molecular Formula C11H14N4O4
Molecular Weight 266.25
Flash Point 310.9ºC
Exact Mass 266.10200
PSA 113.52000
Vapour Pressure 8.74E-15mmHg at 25°C
Index of Refraction 1.796

 Synthetic Route

 Synonyms

6-Methylpurine ribonucleoside
6-D-MPR
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol
6-methylpurine-riboside