1,3-二甲基尿酸
1,3-二甲基尿酸用途
1,3-二甲基尿酸名称
[ CAS 号 ]:
944-73-0
[ 中文名 ]:
1,3-二甲基尿酸
[ 英文名 ]:
1,3-Dimethyluric acid
[中文别名 ]:
[英文别名 ]:
- EINECS 213-410-1
- 1,3-DIMETHYLURIC ACID
- MFCD00009740
1,3-二甲基尿酸生物活性
1,3-二甲基尿酸物理化学性质
[ 密度 ]:
1.63g/cm3
[ 沸点 ]:
520.2ºC at 760mmHg
[ 熔点 ]:
≥300ºC(lit.)
[ 分子式 ]:
C7H8N4O3
[ 分子量 ]:
196.16300
[ 闪点 ]:
268.4ºC
[ 精确质量 ]:
196.06000
[ PSA ]:
92.65000
[ 折射率 ]:
1.675
[ 储存条件 ]:
−20°C
[ 水溶解性 ]:
1 M NH4OH: soluble50mg/mL, clear to slightly hazy, colorless to faintly yellow
1,3-二甲基尿酸MSDS
1,3-二甲基尿酸毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UP0783700
- CHEMICAL NAME :
- 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1,3-dimethyl-
- CAS REGISTRY NUMBER :
- 944-73-0
- BEILSTEIN REFERENCE NO. :
- 0193698
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H8-N4-O3
- MOLECULAR WEIGHT :
- 196.19
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-43463
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-43463
1,3-二甲基尿酸安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危害码 (欧洲) ]:
Xi
[ 安全声明 (欧洲) ]:
S24/25
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
2
[ RTECS号 ]:
UP0783700
[ 海关编码 ]:
2933990090
1,3-二甲基尿酸合成路线
1,3-二甲基尿酸上下游产品
1,3-二甲基尿酸上游产品
1,3-二甲基尿酸下游产品
1,3-二甲基尿酸海关
[ 海关编码 ]: 2933990090
[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
1,3-二甲基尿酸文献
Bioorg. Med. Chem. Lett. 20 , 141-4, (2010)
CTP synthase (CTPS) catalyzes the conversion of UTP to CTP and is a recognized target for the development of anticancer, antiviral, and antiprotozoal agents. Xanthine and related compounds inhibit CTP...
Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic beta-cells.Bioorg. Med. Chem. Lett. 15 , 1181-4, (2005)
Uric acid (1a) suppresses basal insulin release in isolated rat pancreatic islets and inhibition of glucose-stimulated insulin secretion (GSIS) occurs right at hyperuricaemic levels (0.4 mM). Converse...
Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.J. Pharm. Pharmacol. 60(1) , 45-53, (2008)
The types of hepatic cytochrome P450 (CYP) isozymes responsible for the metabolism of theophylline and for the formation of 1,3-dimethyluric acid (1,3-DMU) in rats in-vivo does not seem to have been s...
推荐生产厂家/供应商:
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产品详情:1,3-二甲基尿酸
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥311.0/100mg
¥562.0/250mg
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产品详情:[Perfemiker]1,3-二甲基尿酸,98%
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥211.9/100mg
¥415.9/250mg
¥1180.9/1g
¥5149.9/5g
联系人:阿拉丁李高志
产品详情:1,3-二甲基尿酸
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