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水杨酰肼

水杨酰肼名称

[ CAS 号 ]:
936-02-7

[ 中文名 ]:
水杨酰肼

[ 英文名 ]:
Salicylhydrazide

[中文别名 ]:

[英文别名 ]:

MFCD00007599
2-hydroxybenzohydrazide
EINECS 213-311-3

水杨酰肼物理化学性质

[ 密度 ]:
1.318g/cm3

[ 熔点 ]:
147-150 °C(lit.)

[ 分子式 ]:
C₇H₈N₂O₂

[ 分子量 ]:
152.15100

[ 精确质量 ]:
152.05900

[ PSA ]:
75.35000

[ LogP ]:
1.08690

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 折射率 ]:
1.622

[ 储存条件 ]:
存放于惰性气体之中;避免空气

[ 水溶解性 ]:
可溶于：乙醇,甲醇

水杨酰肼MSDS

水杨酰肼毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO3700000

CHEMICAL NAME :: Salicylic acid, hydrazide

CAS REGISTRY NUMBER :: 936-02-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H8-N2-O2

MOLECULAR WEIGHT :: 152.17

WISWESSER LINE NOTATION :: ZMVR BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - monoamine oxidase

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,259,1961

水杨酰肼安全信息

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ WGK德国 ]:
3

[ RTECS号 ]:
VO3700000

[ 海关编码 ]:
2928000090

水杨酰肼合成路线

水杨酰肼上下游产品

水杨酰肼上游产品

水杨酰肼下游产品

水杨酰肼海关

[ 海关编码 ]: 2928000090

[ 中文概述 ]:
2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

水杨酰肼文献

Synthesis, Characterization, and Anticancer Activity of New Metal Complexes Derived from 2-Hydroxy-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide.

Bioinorg. Chem. Appl. 2015 , 126023, (2015)

Novel metal(II) complexes derived from 2-hydroxy-N'-((Z)-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide ligand (H2L) were synthesized and characterized by elemental and thermal analyses (DTA an...

Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors.

Br. J. Pharmacol. 142 , 97-106 , (2004)

1. A high-throughput assay utilizing the voltage/ion probe reader (VIPR) technology identified salicylidene salicylhydrazide (SCS) as being a potent selective inhibitor of alpha2beta1gamma1 GABA(A) re...

Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.

Bioorg. Med. Chem. Lett. 17(23) , 6472-5, (2007)

The previously discovered salicylhydrazide class of compounds displayed potent HIV-1 integrase (IN) inhibitory activity. The development of this class of compounds as antiretroviral agents was halted ...

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