二甘醇胺

二甘醇胺用途

Amino-PEG2-alcohol is a PEG derivative containing an amino group with a hydroxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

二甘醇胺名称

[ CAS 号 ]:
929-06-6

[ 中文名 ]:
二甘醇胺

[ 英文名 ]:
Diglycolamine

[中文别名 ]:

[英文别名 ]:

Diethylene glycol amine
2,6-DIMETHYLTHIOPHENOL
MFCD00008181
5-Hydroxy-3-oxapentylamine
2-(2-hydroxyethoxy)ethanamine
β-(β-Hydroxyethoxy)ethylamine
diethylene glycol monoamine
Ethanol, 2- (2-aminoethoxy)-
β-Hydroxy-β'-aminodiethyl ether
Ethanol,2-(2-aminoethoxy)

二甘醇胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
221.0±0.0 °C at 760 mmHg

[ 熔点 ]:
-12.5 °C

[ 分子式 ]:
C₄H₁₁NO₂

[ 分子量 ]:
105.136

[ 闪点 ]:
76.6±20.4 °C

[ 精确质量 ]:
105.078979

[ PSA ]:
55.48000

[ LogP ]:
-1.37

[ 外观性状 ]:
透明至非常淡黄色液体

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.449

[ 储存条件 ]:
库房通风低温干燥,与酸、氧化剂分开存放

[ 稳定性 ]:
Stable. Incompatible with acids, strong oxidizing agents. Reacts with carbon dioxide.

[ 水溶解性 ]:
miscible

二甘醇胺MSDS

详细MSDS(安全技术说明书)

二甘醇胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KJ6125000

CHEMICAL NAME :: Ethanol, 2-(2-aminoethoxy)-

CAS REGISTRY NUMBER :: 929-06-6

BEILSTEIN REFERENCE NO. :: 0906728

LAST UPDATED :: 199806

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C4-H11-N-O2

MOLECULAR WEIGHT :: 105.16

WISWESSER LINE NOTATION :: Z2O2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(9),50,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2825 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity)

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(9),50,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1190 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3419 No. of Facilities: 64 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 1967 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3419 No. of Facilities: 787 (estimated) No. of Industries: 13 No. of Occupations: 12 No. of Employees: 5579 (estimated) No. of Female Employees: 861 (estimated)

二甘醇胺安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H312-H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R21;R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S24/25

[ 危险品运输编码 ]:
UN 3055 8/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
KJ6125000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
29221980

二甘醇胺合成路线

详细合成路线

二甘醇胺上下游产品

二甘醇胺上游产品

二甘醇胺下游产品

二甘醇胺制备

DGA可以生产，或与吗啉联产，或作为吗啉生产的副产品回收。

二甘醇胺海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

二甘醇胺文献

The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension.

PLoS ONE 10 , e0136780, (2015)

The surface of aligned, electrospun poly-L-lactic acid (PLLA) fibers was chemically modified to determine if surface chemistry and hydrophilicity could improve neurite extension from chick dorsal root...

Synthesis and biological evaluation of ureido and thioureido derivatives of 2-amino-2-deoxy-D-glucose and related aminoalcohols as N-acetyl-beta-D-hexosaminidase inhibitors.

Carbohydr. Res. 314(1-2) , 47-63, (1998)

Ureido and thioureido derivatives of 2-acetamido-2-deoxy-beta-D-glucose, 1-amino-1-deoxy-D-glucitol and 2-(2-aminoethoxy)ethanol were prepared as N-acetyl-beta-D-hexosaminidase (NAHase) inhibitors and...

Design of quantum dot-conjugated lipids for long-term, high-speed tracking experiments on cell surfaces.

J. Am. Chem. Soc. 130(45) , 15054-62, (2008)

The current study reports the facile design of quantum dot (QD)-conjugated lipids and their application to high-speed tracking experiments on cell surfaces. CdSe/ZnS core/shell QDs with two types of h...

更多文献