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木瓜蛋白酶

木瓜蛋白酶用途

Papain 是肽酶 C1 家族中的一种半胱氨酸蛋白酶,广泛应用于食品、医药、纺织、化妆品等。

木瓜蛋白酶名称

[ CAS 号 ]:
9001-73-4

[ 中文名 ]:
木瓜蛋白酶

[ 英文名 ]:
Papain

[中文别名 ]:

[英文别名 ]:

Velardon
Vermizym
EINECS 232-627-2
MFCD00131791

木瓜蛋白酶生物活性

[ 描述 ]:

Papain 是肽酶 C1 家族中的一种半胱氨酸蛋白酶,广泛应用于食品、医药、纺织、化妆品等。

[ 相关类别 ]:

信号通路 >> 代谢酶/蛋白酶 >> 组织蛋白酶

研究领域 >> 炎症/免疫

天然产物 >> 其他

[体外研究]

木瓜蛋白酶是肽酶C1家族的半胱氨酸蛋白酶,其用于食品,药物,纺织品和化妆品工业。

[参考文献]

[1]. Machado MN, et al. Bone Marrow-Derived Mononuclear Cell Therapy in Papain-Induced Experimental Pulmonary Emphysema. Front Physiol. 2018 Feb 20;9:121.

[相关活性小分子]

木瓜蛋白酶物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 分子式 ]:
C₁₉H₂₉N₇O₆

[ 分子量 ]:
451.477

[ 闪点 ]:
29 °C

[ 精确质量 ]:
451.217926

[ LogP ]:
-1.47

[ 外观性状 ]:
lyophilized powder | almost white

[ 折射率 ]:
1.652

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
H2O: soluble1.2mg/mL | Soluble in water, insoluble in most organic solvents.

木瓜蛋白酶安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H319-H334-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338-P342 + P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R42;R36/37/38

[ 安全声明 (欧洲) ]:
S22;S24;S26;S36/S37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
RU4950000

木瓜蛋白酶制备

1.由木瓜(Caric papaya)的未成熟果实，经提取乳液、凝固、沉降、干燥而成粗制品。一般工业上以粗制品

木瓜蛋白酶文献

Lung injury-dependent oxidative status and chymotrypsin-like activity of skeletal muscles in hamsters with experimental emphysema.

BMC Musculoskelet. Disord. 14 , 39, (2013)

Peripheral skeletal muscle is altered in patients suffering from emphysema and chronic obstructive pulmonary disease (COPD). Oxidative stress have been demonstrated to participate on skeletal muscle l...

Chemomechanical caries removal in primary molars : evaluation of marginal leakage and shear bond strength in bonded restorations--an in vitro study.

J. Clin. Pediatr. Dent. 37(3) , 269-74, (2013)

To evaluate and compare the efficiency, marginal leakage and shear bond strength of Carisolv and Papacarie in primary molars.Freshly extracted 60 human carious primary molars were randomly divided int...

High extracellular Ca2+ stimulates Ca2+-activated Cl- currents in frog parathyroid cells through the mediation of arachidonic acid cascade.

PLoS ONE 6(4) , e19158, (2011)

Elevation of extracellular Ca(2+) concentration induces intracellular Ca(2+) signaling in parathyroid cells. The response is due to stimulation of the phospholipase C/Ca(2+) pathways, but the direct m...

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