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苯芴醇

苯芴醇用途

Lumefantrine是一种抗疟疾药物, 与Artemether联用, 作为一线和二线抗疟药。

苯芴醇名称

[ CAS 号 ]:
82186-77-4

[ 中文名 ]:
苯芴醇

[ 英文名 ]:
Lumefantrine

[中文别名 ]:

[英文别名 ]:

Benflumetol
Lumefantrine

苯芴醇生物活性

[ 描述 ]:

Lumefantrine是一种抗疟疾药物, 与Artemether联用, 作为一线和二线抗疟药。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[参考文献]

[1]. Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14(1):423.

[相关活性小分子]

苯芴醇物理化学性质

[ 密度 ]:
1.252

[ 沸点 ]:
642.5±55.0 °C at 760 mmHg

[ 熔点 ]:
129-131ºC

[ 分子式 ]:
C₃₀H₃₂Cl₃NO

[ 分子量 ]:
528.940

[ 闪点 ]:
342.3±31.5 °C

[ 精确质量 ]:
527.154968

[ PSA ]:
23.47000

[ LogP ]:
11.37

[ 外观性状 ]:
黄色固体

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.634

[ 储存条件 ]:
Refrigerator

苯芴醇MSDS

详细MSDS(安全技术说明书)

苯芴醇安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2922199090

苯芴醇海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

苯芴醇文献

Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships.

Immunology 145(1) , 71-81, (2015)

This study examined specific antibody and T-cell responses associated with experimental malaria infection or malaria vaccination, in malaria-naive human volunteers within phase I/IIa vaccine trials, w...

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity.

Malaria Journal 13 , 359, (2014)

Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolis...

Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions.

J. Clin. Microbiol. 53 , 3296-303, (2015)

Flow cytometry is an objective method for conducting in vitro antimalarial sensitivity assays with increasing potential for application in field sites. We examined in vitro susceptibility to seven ant...

更多文献

苯芴醇

苯芴醇用途

苯芴醇名称

苯芴醇生物活性

苯芴醇物理化学性质

苯芴醇MSDS

详细MSDS(安全技术说明书)

苯芴醇安全信息

苯芴醇海关

苯芴醇文献

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