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氢溴酸西酞普兰

氢溴酸西酞普兰用途

Citalopram盐酸盐是选择性的血清素再摄取抑制剂 (SSRI) 类的抗抑郁药, 已被FDA批准用于治疗抑郁症。

氢溴酸西酞普兰名称

[ CAS 号 ]:
59729-32-7

[ 中文名 ]:
氢溴酸西酞普兰

[ 英文名 ]:
Citalopram hydrobromide

[中文别名 ]:

[英文别名 ]:

Lupram
EINECS 261-890-6
Sepram
Apertia
Lu-10-171
Citalopram hydrobromide
Lu-10-171B
Elopram
Cipram
MFCD02101306

氢溴酸西酞普兰生物活性

[ 描述 ]:

Citalopram盐酸盐是选择性的血清素再摄取抑制剂 (SSRI) 类的抗抑郁药, 已被FDA批准用于治疗抑郁症。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

信号通路 >> 神经信号通路 >> 5-羟色胺转运蛋白

研究领域 >> 神经疾病

[参考文献]

[1]. Cui R, et al. Effects of noradrenergic and serotonergic systems on risk-based decision-making and center arena activity in open field in rats. Eur J Pharmacol. 2018 Sep 27. pii: S0014-2999(18)30566-1.

[相关活性小分子]

氢溴酸西酞普兰物理化学性质

[ 沸点 ]:
182-188ºC

[ 熔点 ]:
182-188ºC

[ 分子式 ]:
C₂₀H₂₂BrFN₂O

[ 分子量 ]:
405.304

[ 闪点 ]:
212.8ºC

[ 精确质量 ]:
404.089935

[ PSA ]:
36.26000

[ LogP ]:
4.77108

[ 外观性状 ]:
白色结晶粉末

[ 储存条件 ]:
库房通风低温干燥,与醇,胺,碱类,含水物品分开储运

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

氢溴酸西酞普兰MSDS

氢溴酸西酞普兰安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P210-P260-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
F,T

[ 风险声明 (欧洲) ]:
11-23/24/25-39/23/24/25

[ 安全声明 (欧洲) ]:
7-16-36/37-45

[ 危险品运输编码 ]:
UN 3249

[ RTECS号 ]:
NP6313500

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2932999099

氢溴酸西酞普兰合成路线

氢溴酸西酞普兰上下游产品

氢溴酸西酞普兰上游产品

氢溴酸西酞普兰下游产品

氢溴酸西酞普兰海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

氢溴酸西酞普兰文献

Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU.

J. Chromatogr. A. 1418 , 140-9, (2015)

The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of...

Magnetic solid phase extraction coupled with desorption corona beam ionization-mass spectrometry for rapid analysis of antidepressants in human body fluids.

Analyst 140 , 5662-70, (2015)

Ambient ionization techniques show good potential in rapid analysis of target compounds. However, a direct application of these ambient ionization techniques for the determination of analytes in a com...

Salt effects in electromembrane extraction.

J. Chromatogr. A. 1347 , 1-7, (2014)

Electromembrane extraction (EME) was performed on samples containing substantial amounts of NaCl to investigate how the presence of salts affected the recovery, repeatability, and membrane current in ...

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