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六氢吡啶-alpha-羧酸

六氢吡啶-alpha-羧酸用途

【用途一】
用作医药中间体

六氢吡啶-alpha-羧酸名称

[ CAS 号 ]:
535-75-1

[ 中文名 ]:
DL-哌啶甲酸

[ 英文名 ]:
Pipecolinic acid

[中文别名 ]:

[英文别名 ]:

Dihydrobaikiaine
UNII:H254GW7PVV
(±)-Piperidine-2-carboxylic acid
DL-Pipecolinic acid
DL-Pipecolinicacid
Pipecolinic acid
6-CARBOXYPIPERIDINE
DL-2-Piperidinecarboxylic acid
(±)-Pipecolinic acid
Pipecolic acid

六氢吡啶-alpha-羧酸生物活性

[ 描述 ]:

Pipecolic acid是赖氨酸的代谢产物。

[ 相关类别 ]:

研究领域 >> 感染

天然产物 >> 酸和醛

研究领域 >> 代谢疾病

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. He M, et al. Pipecolic acid in microbes: biosynthetic routes and enzymes. J Ind Microbiol Biotechnol. 2006 Jun;33(6):401-7.

[相关活性小分子]

六氢吡啶-alpha-羧酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
265.8±33.0 °C at 760 mmHg

[ 熔点 ]:
268-278ºC

[ 分子式 ]:
C₆H₁₁NO₂

[ 分子量 ]:
129.157

[ 闪点 ]:
114.5±25.4 °C

[ 精确质量 ]:
129.078979

[ PSA ]:
49.33000

[ LogP ]:
0.00

[ 外观性状 ]:
白色至淡米色细结晶粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.479

[ 储存条件 ]:
室温，密封

[ 水溶解性 ]:
soluble

六氢吡啶-alpha-羧酸MSDS

详细MSDS(安全技术说明书)

六氢吡啶-alpha-羧酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TK6021000

CHEMICAL NAME :: Pipecolic acid

CAS REGISTRY NUMBER :: 535-75-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H11-N-O2

MOLECULAR WEIGHT :: 129.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CEXPB9 Clinical and Experimental Pharmacology and Physiology. (Blackwell Scientific Publications, (Australia) Pty Ltd., 107 Barry St., Carlton, Vic. 3053, Australia) V.1- 1974- Volume(issue)/page/year: 21,997,1994

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,1343,1968

六氢吡啶-alpha-羧酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TK6021000

[ 海关编码 ]:
2933399090

六氢吡啶-alpha-羧酸上下游产品

六氢吡啶-alpha-羧酸上游产品

六氢吡啶-alpha-羧酸下游产品

六氢吡啶-alpha-羧酸海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

六氢吡啶-alpha-羧酸文献

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.

J. Chromatogr. A. 562(1-2) , 125-38, (1991)

Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease...

ECNI GC-MS analysis of picolinic and quinolinic acids and their amides in human plasma, CSF, and brain tissue.

Adv. Exp. Med. Biol. 527 , 705-12, (2003)

To study the complex inter-relationships between inflammatory and apoptotic responses and the kynurenine pathway, we have utilized electron-capture negative ion mass spectrometry to develop trace anal...

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