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2-甲氧基-2,4-二苯基-3(2H)-呋喃酮

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮用途

2-甲氧基-2,4-二苯基呋喃-3-酮是一种荧光化合物,可用于标记明胶作为底物,通过酶谱法检测明胶降解MMP-2和MMP-9[1]。

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮名称

[ CAS 号 ]:
50632-57-0

[ 中文名 ]:
2-甲氧基-2,4-二苯基-3(2H)-呋喃酮

[ 英文名 ]:
2-Methoxy-2,4-diphenyl-3(2H)-furanone

[中文别名 ]:

2,4-二苯基-2-甲氧基-3(2H)-呋喃酮

[英文别名 ]:

2-Methoxy-2,4-diphenylfuran-3(2H)-one
MFCD00036834
3(2H)-Furanone, 2-methoxy-2,4-diphenyl-
2-Mdpf
2-Methoxy-2,4-diphenyl-3(2H)-furanone
MDPF
2,4-Diphenyl-2-methoxy-3(2H)-furanone,MDPF
2-methoxy-2,4-diphenyl-furan-3-one

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮生物活性

[ 描述 ]:

2-甲氧基-2,4-二苯基呋喃-3-酮是一种荧光化合物,可用于标记明胶作为底物,通过酶谱法检测明胶降解MMP-2和MMP-9[1]。

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 炎症/免疫

信号通路 >> 代谢酶/蛋白酶 >> MMP

[参考文献]

[1]. Peter Jackson. Detection of phosphoproteins. WO2006070180.

[2]. Danqing Min, et al. 2-Methoxy-2,4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: a rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases. Electrophoresis. 20

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
426.6±45.0 °C at 760 mmHg

[ 熔点 ]:
96ºC

[ 分子式 ]:
C₁₇H₁₄O₃

[ 分子量 ]:
266.291

[ 闪点 ]:
203.6±15.1 °C

[ 精确质量 ]:
266.094299

[ PSA ]:
35.53000

[ LogP ]:
3.48

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.618

[ 储存条件 ]:
2-8°C

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮MSDS

详细MSDS(安全技术说明书)

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2932190090

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮上下游产品

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮上游产品

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮下游产品

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮海关

[ 海关编码 ]: 2932190090

[ 中文概述 ]:
2932190090 其他结构上有非稠合呋喃环化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-甲氧基-2,4-二苯基-3(2H)-呋喃酮文献

Proteolytic activity and cytokine up-regulation by non-albicans Candida albicans.

Arch. Microbiol. 197(4) , 533-7, (2015)

Mouth is an important source of infections and oral infections such as Candida infections increase the risk of mortality. Our purpose was to investigate differences in proteolytic activity of non-albi...

Fluorescent labeling of proteins with nile red and 2-methoxy-2,4-diphenyl-3(2H)-furanone: physicochemical basis and application to the rapid staining of sodium dodecyl sulfate polyacrylamide gels and Western blots.

Electrophoresis 22(5) , 874-80, (2001)

The fluorescent hydrophobic dye Nile red allows the rapid, sensitive, and general staining of proteins in sodium dodecyl sulfate (SDS)-polyacrylamide gels. Nile red staining does not preclude further ...

Rapid imaging, using a cooled charge-coupled-device, of fluorescent two-dimensional polyacrylamide gels produced by labelling proteins in the first-dimensional isoelectric focusing gel with the fluorophore 2-methoxy-2,4-diphenyl-3(2H)furanone.

Electrophoresis 9(7) , 330-9, (1988)

A new method for visualising proteins in two-dimensional polyacrylamide gels was developed. Proteins were labelled with the fluorophore 2-methoxy-2,4-diphenyl-3(2H)furanone (MDPF) while present in the...

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