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S-苯汞基酸

S-苯汞基酸用途

苯的代谢物S-苯巯基尿酸可用作生物标志物,通过GC、HPLC(UV或荧光检测)、GC-MS、LC-MS/MS或免疫测定[1]进行鉴定。

S-苯汞基酸名称

[ CAS 号 ]:
4775-80-8

[ 中文名 ]:
S-苯汞基酸

[ 英文名 ]:
S-Phenylmercapturic Acid

[中文别名 ]:

N-乙酰基-S-苯基-L-半胱氨酸

[英文别名 ]:

s-phenylmercapturic acid

S-苯汞基酸生物活性

[ 描述 ]:

苯的代谢物S-苯巯基尿酸可用作生物标志物,通过GC、HPLC(UV或荧光检测)、GC-MS、LC-MS/MS或免疫测定[1]进行鉴定。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Peter B Farmer, et al. The use of S-phenylmercapturic acid as a biomarker in molecular epidemiology studies of benzene. Chem Biol Interact. 2005 May 30;153-154:97-102.

S-苯汞基酸物理化学性质

[ 沸点 ]:
494.5ºC at 760 mmHg

[ 熔点 ]:
110-112ºC

[ 分子式 ]:
C₁₀H₁₃NO₂S

[ 分子量 ]:
211.28100

[ 闪点 ]:
252.9ºC

[ 精确质量 ]:
211.06700

[ PSA ]:
74.63000

[ LogP ]:
1.84220

[ 储存条件 ]:
-20?C Freezer

S-苯汞基酸MSDS

S-苯汞基酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2930909090

S-苯汞基酸合成路线

S-苯汞基酸上下游产品

S-苯汞基酸上游产品

S-苯汞基酸下游产品

S-苯汞基酸海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

S-苯汞基酸文献

Influence of genetic polymorphism on t,t-MA/S-PMA ratio in 301 benzene exposed subjects.

Toxicol. Lett. 231(2) , 205-12, (2014)

This study investigated the effect of polymorphic genes GSTT1, GSTM1, GSTA1, EHPX1, NQO1, CYP2E1, CYP1A and MPO on the urinary concentrations and ratio (R) of the benzene metabolites trans,trans-mucon...

Metabolic polymorphisms and biomarkers of effect in the biomonitoring of occupational exposure to low-levels of benzene: state of the art.

Toxicol. Lett. 231(2) , 194-204, (2014)

Current levels of occupational exposure to benzene, a genotoxic human carcinogen, in Western countries are reduced by two-three orders of magnitude (from ppm to ppb) as compared to the past. However, ...

Urinary trans, trans-muconic acid and S-phenylmercapturic acid are indicative of exposure to urban benzene pollution during childhood.

Sci. Total Environ. 435-436 , 115-23, (2012)

The aims of the study were to evaluate the feasibility of urinary trans, trans-muconic acid (u-t,t-MA) and urinary S-phenylmercapturic acid (u-SPMA) as markers of exposure to urban benzene pollution f...

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