4-羟基-3-甲氧基肉桂醛

4-羟基-3-甲氧基肉桂醛用途

Coniferaldehyde (Ferulaldehyde) 可从 Vitex rotundifolia 果实中分离。Coniferaldehyde 是血红素加氧酶-1 (HO-1) 的有效诱导剂,具有抗炎作用。在 RAW264.7 巨噬细胞中,Coniferaldehyde 通过 PKCα/βII/Nrf-2/HO-1 依赖性途径来抑制 LPS 诱导的细胞凋亡。

4-羟基-3-甲氧基肉桂醛名称

[ CAS 号 ]:
458-36-6

[ 中文名 ]:
4-羟基-3-甲氧基肉桂醛

[ 英文名 ]:
coniferyl aldehyde

[中文别名 ]:

[英文别名 ]:

Ferulaldehyde
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
Ferulyl aldehyde
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl), (E)-
4-hydroxy-3-methoxy-benzaldehyde
MFCD00075811
4-hydroxy-3-methoxy-cinnamon-aldehyde
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
coniferaldehyde

4-羟基-3-甲氧基肉桂醛生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Kim KM, et al. Coniferaldehyde inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Environ Toxicol Pharmacol. 2016 Dec;48:85-93.

4-羟基-3-甲氧基肉桂醛物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
338.8±27.0 °C at 760 mmHg

[ 熔点 ]:
80-82ºC(lit.)

[ 分子式 ]:
C₁₀H₁₀O₃

[ 分子量 ]:
178.185

[ 闪点 ]:
136.8±17.2 °C

[ 精确质量 ]:
178.062988

[ PSA ]:
46.53000

[ LogP ]:
1.35

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.593

[ 储存条件 ]:
2-8°C

4-羟基-3-甲氧基肉桂醛MSDS

4-羟基-3-甲氧基肉桂醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2912499000

4-羟基-3-甲氧基肉桂醛合成路线

4-羟基-3-甲氧基肉桂醛上下游产品

4-羟基-3-甲氧基肉桂醛上游产品

4-羟基-3-甲氧基肉桂醛下游产品

4-羟基-3-甲氧基肉桂醛海关

[ 海关编码 ]: 2912499000

[ 中文概述 ]:
2912499000. 其他醛醚、醛酚及含其他含氧基的醛. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 四聚甲醛报明外观

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

4-羟基-3-甲氧基肉桂醛文献

A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry.

J. Mass Spectrom. 49(8) , 665-73, (2014)

Imaging mass spectrometry (IMS) studies increasingly focus on endogenous small molecular weight metabolites and consequently bring special analytical challenges. Since analytical tissue blanks do not ...

Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry.

J. Am. Soc. Mass Spectrom. 22(8) , 1409-19, (2011)

Isoniazid (INH) is an important component of front-line anti-tuberculosis therapy with good serum pharmacokinetics but unknown ability to penetrate tuberculous lesions. However, endogenous background ...

Antifungal synergistic effect of scopoletin, a hydroxycoumarin isolated from Melia azedarach L. fruits.

J. Agric. Food Chem. 53(8) , 2922-7, (2005)

In the continuous search for antifungal compounds from plants, the hydroxycoumarin scopoletin (1) was isolated from seed kernels of Melia azedarach L. from which three other compounds, vanillin (2), 4...

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