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2-异丙基苹果酸

2-异丙基苹果酸用途

α-苹果酸异丙酯(α-IPM)是酵母中的亮氨酸生物合成前体[1]。

2-异丙基苹果酸名称

[ CAS 号 ]:
3237-44-3

[ 中文名 ]:
2-异丙基苹果酸

[ 英文名 ]:
2-HYDROXY-2-ISOPROPYLSUCCINIC ACID

[英文别名 ]:

2-hydroxy-2-isopropyl-succinic acid
2-HYDROXY-2-ISOPROPYLSUCCINIC ACID
2-Hydroxy-2-isopropyl-bernsteinsaeure
MFCD00075003
2-Hydroxy-2-isopropylbutanedioic acid

2-异丙基苹果酸生物活性

[ 描述 ]:

α-苹果酸异丙酯(α-IPM)是酵母中的亮氨酸生物合成前体[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

α-苹果酸异丙酯(500μM)增加LEU3蛋白(Leu3p)依赖性转录[1]。α-苹果酸异丙酯(10mM,48小时)增加前脂肪细胞(30A5)中报告基因的表达[2]。

2-异丙基苹果酸物理化学性质

[ 密度 ]:
1.342g/cm3

[ 沸点 ]:
306.4ºC at 760mmHg

[ 熔点 ]:
144-146ºC(lit.)

[ 分子式 ]:
C₇H₁₂O₅

[ 分子量 ]:
176.16700

[ 闪点 ]:
153.3ºC

[ 精确质量 ]:
176.06800

[ PSA ]:
94.83000

[ 外观性状 ]:
固体

[ 储存条件 ]:
室温

2-异丙基苹果酸MSDS

2-异丙基苹果酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26-37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2918199090

2-异丙基苹果酸合成路线

2-异丙基苹果酸上下游产品

2-异丙基苹果酸上游产品

2-异丙基苹果酸下游产品

2-异丙基苹果酸制备

1. 烟草：OR，44；OR，26；BU，26。

2-异丙基苹果酸海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

2-异丙基苹果酸文献

Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes.

Metabolomics 11 , 1277-1286, (2015)

Biomarkers for the development of type 2 diabetes (T2D) are useful for prediction and intervention of the disease at earlier stages. In this study, we performed a longitudinal study of changes in meta...

Human metabolic responses to chronic environmental polycyclic aromatic hydrocarbon exposure by a metabolomic approach.

J. Proteome Res. 14 , 2583-93, (2015)

The toxicities of polycyclic aromatic hydrocarbons (PAHs) have been extensively explored due to their carcinogenic and mutagenic potency; however, little is known about the metabolic responses to chro...

A potential tool for diagnosis of male infertility: Plasma metabolomics based on GC-MS.

Talanta 147 , 82-9, (2015)

Male infertility has become an important public health problem worldwide. Nowadays the diagnosis of male infertility frequently depends on the results of semen quality or requires more invasive surgic...

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