SL327
SL327用途
SL327名称
[ CAS 号 ]:
305350-87-2
[ 中文名 ]:
ALPHA-[氨基[(4-氨基苯基)硫代]亚甲基]-2-(三氟甲基)苯乙腈
[ 英文名 ]:
SL-327
[英文别名 ]:
- MEK1/2 Inhibitor
- HMS3229K18
- SL327
- SL 327
SL327生物活性
[ 描述 ]:
[ 相关类别 ]:
[ 靶点 ]
MEK1:180 nM (IC50)
MEK2:220 nM (IC50)
[体外研究]
[体内研究]
[激酶实验]
[动物实验]
[参考文献]
[相关活性小分子]
SL327物理化学性质
[ 密度 ]:
1.4±0.1 g/cm3
[ 沸点 ]:
512.6±50.0 °C at 760 mmHg
[ 熔点 ]:
127-128.2ºC
[ 分子式 ]:
C16H12F3N3S
[ 分子量 ]:
335.347
[ 闪点 ]:
263.8±30.1 °C
[ 精确质量 ]:
335.070404
[ PSA ]:
101.13000
[ LogP ]:
1.95
[ 外观性状 ]:
solid | white
[ 蒸汽压 ]:
0.0±1.3 mmHg at 25°C
[ 折射率 ]:
1.631
[ 储存条件 ]:
2-8°C
[ 水溶解性 ]:
DMSO: 32 mg/mL
SL327MSDS
SL327安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
3
SL327文献
Oncogene 34 , 3985-93, (2015)
Oncolytic viruses exploit common molecular changes in cancer cells, which are not present in normal cells, to target and kill cancer cells. Ras transformation and defects in type I interferon (IFN)-me...
Repeated stimulation of dopamine D1-like receptor and hyperactivation of mTOR signaling lead to generalized seizures, altered dentate gyrus plasticity, and memory deficits.Hippocampus 24(12) , 1466-81, (2014)
The acute activation of the dopamine D1-like receptors (D1R) is involved in a plethora of functions ranging from increased locomotor activity to the facilitation of consolidation, storage, and retriev...
Alcohol alters the activation of ERK1/2, a functional regulator of binge alcohol drinking in adult C57BL/6J mice.Alcohol. Clin. Exp. Res. 39(3) , 463-75, (2015)
Binge alcohol drinking is a particularly risky pattern of alcohol consumption that often precedes alcohol dependence and addiction. The transition from binge alcohol drinking to alcohol addiction like...
推荐生产厂家/供应商:
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:SL327
公司名:上海脉铂医药科技有限公司
区域:上海市嘉定区
价格:
¥需询单/1g
¥7500.0/500mg
¥2500.0/100mg
¥700.0/100mg
联系人:李先生
产品详情:SL327
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥399.9/10mg
¥720.9/1ml
¥4589.9/250mg
¥1299.9/50mg
联系人:阿拉丁李高志
产品详情:SL-327
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥720.0/10mg
联系人:夏言
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相关化合物
[SL327]化源网提供SL327CAS号305350-87-2,SL327MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询SL327上化源网,专业又轻松。>>电脑版:SL327
标题:305350-87-2_SL327CAS号:305350-87-2_SL327【结构式 性质 英文】 - 化源网 地址:https://www.chemsrc.com/amp/cas/305350-87-2_671784.html