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樱花亭

樱花亭用途

Sakuranetin 是一种大米黄酮类植物抗毒素,具有很强的抗真菌活性。Sakuranetin 具有抗炎和抗氧化作用,能够改善 LPS 诱导的急性肺损伤。

樱花亭名称

[ CAS 号 ]:
2957-21-3

[ 中文名 ]:
樱花亭

[ 英文名 ]:
Sakuranetin

[中文别名 ]:

[英文别名 ]:

4',5-Dihydroxy-7-methoxyflavanone
(S)-(-)-4',5-dihydroxy-7-methoxyflavanone
4',5-DIHYDROXY-7-METHOXYFLAVONE
Naringenin 7-O-methyl ether
5,4'-dihydroxy-7-methoxyflavanone
(2S)-sakuranetin
7-O-Methylnaringenin
naringenin 7-methylether
(S)-(-)-4',5-Dihydroxy-7-methoxy-flavanone
Sakuranetin

樱花亭生物活性

[ 描述 ]:

Sakuranetin 是一种大米黄酮类植物抗毒素,具有很强的抗真菌活性。Sakuranetin 具有抗炎和抗氧化作用,能够改善 LPS 诱导的急性肺损伤。

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 真菌

研究领域 >> 炎症/免疫

[参考文献]

[1]. Hasegawa M, et al. Analysis on blast fungus-responsive characters of a flavonoid phytoalexin sakuranetin; accumulation in infected rice leaves, antifungal activity and detoxification by fungus. Molecules. 2014 Aug 4;19(8):11404-18.

[2]. Bittencourt-Mernak MI, et al. Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L217-L230.

樱花亭物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
555.9±50.0 °C at 760 mmHg

[ 熔点 ]:
153-154ºC

[ 分子式 ]:
C₁₆H₁₄O₅

[ 分子量 ]:
286.28

[ 闪点 ]:
212.4±23.6 °C

[ 精确质量 ]:
286.084137

[ PSA ]:
75.99000

[ LogP ]:
3.37

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.638

[ 储存条件 ]:
2-8℃

樱花亭安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 危险品运输编码 ]:
NONH for all modes of transport

樱花亭文献

A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia.

Fitoterapia 98 , 11-21, (2014)

The alpha7 nicotinic acetylcholine receptor (nAChR) is a potential target in neuroinflammation. Screening a plant extract library identified Solidago nemoralis as containing methyl-quercetin derivativ...

In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC. (Asteraceae).

Exp. Parasitol. 130(2) , 141-5, (2012)

Leishmaniasis and Chagas' are parasitic protozoan diseases that affect the poorest population in the world, causing a high mortality and morbidity. As a result of highly toxic and long-term treatments...

Isoprenylated flavonoid and adipogenesis-promoting constituents of Dodonaea viscosa.

J. Nat. Prod. 75(4) , 699-706, (2012)

Ten new isoprenylated flavonol derivatives, dodoviscins A-J (1-10), and seven known compounds (11-17) were isolated from the aerial parts of Dodonaea viscosa. Compounds 1, 2, 4, 5, 7-9, 5,7,4'-trihydr...

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樱花亭