<生产厂家价格>

AL 8810

AL 8810用途

AL-8810是PGF2α的11β-氟类似物,是PGF2α受体(FP受体)的有效和选择性拮抗剂[1]。

AL 8810名称

[ CAS 号 ]:
246246-19-5

[ 英文名 ]:
AL 8810

[英文别名 ]:

al 8810

AL 8810生物活性

[ 描述 ]:

AL-8810是PGF2α的11β-氟类似物,是PGF2α受体(FP受体)的有效和选择性拮抗剂[1]。

[ 相关类别 ]:

研究领域 >> 内分泌

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体

[参考文献]

[1]. Griffin BW, et al. AL-8810: a novel prostaglandin F2 alpha analog with selective antagonist effects at the prostaglandin F2 alpha (FP) receptor. J Pharmacol Exp Ther. 1999 Sep;290(3):1278-84.

AL 8810物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
594.6±50.0 °C at 760 mmHg

[ 分子式 ]:
C₂₄H₃₁FO₄

[ 分子量 ]:
402.499

[ 闪点 ]:
313.4±30.1 °C

[ 精确质量 ]:
402.220642

[ PSA ]:
77.76000

[ LogP ]:
4.00

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.584

[ 储存条件 ]:
-20°C，密闭，干燥

AL 8810MSDS

详细MSDS(安全技术说明书)

AL 8810安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

AL 8810文献

Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential.

J. Lipid Res. 55(12) , 2479-90, (2014)

Arachidonic acid (AA) is a major PUFA that has been implicated in the regulation of adipogenesis. We examined the effect of a short exposure to AA at different stages of 3T3-L1 adipocyte differentiati...

Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction.

Respir. Res. 6 , 85, (2005)

In addition to their proliferative and differentiating effects, several growth factors are capable of inducing a sustained airway smooth muscle (ASM) contraction. These contractile effects were previo...

更多文献