<生产厂家价格>

1-氨基环丁甲酸

1-氨基环丁甲酸用途

1-Aminocyclobutanecarboxylic acid 是作用于 NR1 甘氨酸位点的 NMDA 受体部分激动剂。

1-氨基环丁甲酸名称

[ CAS 号 ]:
22264-50-2

[ 中文名 ]:
1-氨基环丁烷羧酸

[ 英文名 ]:
1-Aminocyclobutanecarboxylic acid

[中文别名 ]:

[英文别名 ]:

N-Methylquipazine dimaleate
1-amino-cyclobutanecarboxylicaci
ACBC-OH
MFCD00661068
cb1700
AC4C-OH
Cyclobutanecarboxylic acid, 1-amino-
1-Aminocyclobutaneca
1-Amino-1-carboxycyclobutane
1-Amino-1-cyclobutanecarboxylic acid

1-氨基环丁甲酸生物活性

[ 描述 ]:

1-Aminocyclobutanecarboxylic acid 是作用于 NR1 甘氨酸位点的 NMDA 受体部分激动剂。

[ 相关类别 ]:

信号通路 >> 神经信号通路 >> iGluR

研究领域 >> 神经疾病

信号通路 >> 跨膜转运 >> iGluR

[参考文献]

[1]. Atsushi Inanobe, et al. Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron. 2005 Jul 7;47(1):71-84.

1-氨基环丁甲酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
241.1±23.0 °C at 760 mmHg

[ 熔点 ]:
261ºC (dec.)

[ 分子式 ]:
C₅H₉NO₂

[ 分子量 ]:
115.131

[ 闪点 ]:
99.6±22.6 °C

[ 精确质量 ]:
115.063332

[ PSA ]:
63.32000

[ LogP ]:
-0.62

[ 外观性状 ]:
白色至黄褐色的粉末,晶体,结晶粉末,和/或带有大块

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.540

[ 储存条件 ]:
Store at RT

1-氨基环丁甲酸MSDS

1-氨基环丁甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU1336000

CHEMICAL NAME :: Cyclobutanecarboxylic acid, 1-amino-

CAS REGISTRY NUMBER :: 22264-50-2

BEILSTEIN REFERENCE NO. :: 2802253

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H9-N-O2

MOLECULAR WEIGHT :: 115.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

1-氨基环丁甲酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
GU1336000

[ 海关编码 ]:
2922499990

1-氨基环丁甲酸合成路线

1-氨基环丁甲酸上下游产品

1-氨基环丁甲酸上游产品

1-氨基环丁甲酸下游产品

1-氨基环丁甲酸制备

1-氨基环丁甲酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

1-氨基环丁甲酸文献

[Change in the level of 1-aminochloropropane-1-carbonic acid. Activity of a protein inhibitor of polygalacturonase, intensity of formation of oligouronides in apples during ripening and treatment with haloethane derivatives and aminoethoxyvinylglycine].

Prikl. Biokhim. Mikrobiol. 39(4) , 461-4, (2003)

We studied changes in the intensity of ethylene release and accumulation of 1-aminocyclopropane-1-carboxylic acid during ripening of two apple varieties characterized by various physiological states a...

Glycine antagonist action of 1-aminocyclobutane-1-carboxylate (ACBC) in Xenopus oocytes injected with rat brain mRNA.

Eur. J. Pharmacol. 167(2) , 291-4, (1989)

ACBC has been reported to have the binding profile of an antagonist at the glycine site of the NMDA receptor. In Xenopus oocytes injected with rat brain mRNA, we have confirmed the antagonist action o...

Ethylene biosynthesis: processing of a substrate analog supports a radical mechanism for the ethylene-forming enzyme.

Chem. Biol. 5(1) , 49-57, (1998)

The chemical mechanism of the final step of ethylene biosynthesis (the conversion of 1-aminocyclopropanecarboxylic acid, ACC, to ethylene by ACC oxidase, the ethylene-forming enzyme, EFE) is poorly un...

更多文献