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5-甲基尿甙

5-甲基尿甙用途

5-Methyluridine是一种在人体液中发现的内源性甲基化核苷。

5-甲基尿甙名称

[ CAS 号 ]:
1463-10-1

[ 中文名 ]:
5-甲基尿甙

[ 英文名 ]:
5-Methyluridine

[中文别名 ]:

[英文别名 ]:

5-Methyl Uridine
5-methyl-D-uridine
ribothymidine
Thymine riboside
Uridine, 5-methyl-
EINECS 215-973-9
5-methyl-Uridine
1-b-D-Ribofuranosylthymine
Ribosylthymine
MFCD00006535

5-甲基尿甙生物活性

[ 描述 ]:

5-Methyluridine是一种在人体液中发现的内源性甲基化核苷。

[ 相关类别 ]:

天然产物 >> 生物碱

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Yang TH, et al. Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities. Nutr Cancer. 2006;55(2):224-31.

[相关活性小分子]

5-甲基尿甙物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 熔点 ]:
183-184 °C(lit.)

[ 分子式 ]:
C₁₀H₁₄N₂O₆

[ 分子量 ]:
258.228

[ 精确质量 ]:
258.085175

[ PSA ]:
124.78000

[ LogP ]:
-1.02

[ 外观性状 ]:
白色粉末

[ 折射率 ]:
1.619

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
水溶性：可溶

5-甲基尿甙MSDS

5-甲基尿甙安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
T+: Very toxic;

[ 风险声明 (欧洲) ]:
R26/27/28

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2934999090

5-甲基尿甙合成路线

5-甲基尿甙上下游产品

5-甲基尿甙上游产品

5-甲基尿甙下游产品

5-甲基尿甙海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-甲基尿甙文献

Metabolome analysis via comprehensive two-dimensional liquid chromatography: identification of modified nucleosides from RNA metabolism.

Anal. Bioanal. Chem 407(13) , 3555-66, (2015)

Modified nucleosides derived from the RNA metabolism constitute an important chemical class, which are discussed as potential biomarkers in the detection of mammalian breast cancer. Not only the varia...

Exometabolom analysis of breast cancer cell lines: Metabolic signature.

Sci. Rep. 5 , 13374, (2015)

Cancer cells show characteristic effects on cellular turnover and DNA/RNA modifications leading to elevated levels of excreted modified nucleosides. We investigated the molecular signature of differen...

Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography.

J. Chromatogr. A. 1403 , 54-62, (2015)

The objective of this study was to model the retention of nucleosides and pterins in hydrophilic interaction liquid chromatography (HILIC) via QSRR-based approach. Two home-made (Amino-P-C18, Amino-P-...

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