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磺基乙酸

磺基乙酸名称

[ CAS 号 ]:
123-43-3

[ 中文名 ]:
磺基乙酸

[ 英文名 ]:
sulfoacetic acid

[中文别名 ]:

[英文别名 ]:

SULFOACETIC ACID
2-sulfoethanoic acid
2-SULFOACETIC ACID
kyselinasulfooctova
sulfonic acetic acid
sulfo-aceticaci
sulfo-acetic acid
SULFOETHANOIC ACID
Methan-carbonsaeure-sulfonsaeure
Sulfo-essigsaeure

磺基乙酸物理化学性质

[ 密度 ]:
1.875g/cm3

[ 熔点 ]:
81-88 °C(lit.)

[ 分子式 ]:
C₂H₄O₅S

[ 分子量 ]:
140.11500

[ 精确质量 ]:
139.97800

[ PSA ]:
100.05000

[ LogP ]:
0.03960

[ 折射率 ]:
1.536

[ 储存条件 ]:
室温，密闭，干燥

磺基乙酸MSDS

磺基乙酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AJ4900000

CHEMICAL NAME :: Acetic acid, sulfo-

CAS REGISTRY NUMBER :: 123-43-3

BEILSTEIN REFERENCE NO. :: 1764390

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C2-H4-O5-S

MOLECULAR WEIGHT :: 140.12

WISWESSER LINE NOTATION :: WSQ1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1051,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1051,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,60,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1570 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,60,1949

磺基乙酸安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H312-H314-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C: Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
26-27-28-36/37/39-45

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
AJ4900000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2915900090

磺基乙酸合成路线

磺基乙酸上下游产品

磺基乙酸上游产品

磺基乙酸下游产品

磺基乙酸海关

[ 海关编码 ]: 2915900090

[ 中文概述 ]:
2915900090. 其他饱和无环一元羧酸及其酸酐（酰卤、过氧）化物、过氧酸及其卤化、硝化、磺化、亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

磺基乙酸文献

Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: synthesis and structure-activity relationships of novel series of sulfonamides, acylphosphonamides and acylphosphoramidates.

Bioorg. Med. Chem. Lett. 8(3) , 289-94, (1998)

Sulfoacetic acid, phosphoramidate, and phosphoramide analogs of the ACAT inhibitors, CI-999 and CI-1011 were synthesized. The structure-activity relationships of these compounds as ACAT inhibitors are...

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