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2-硝基-4-氨基苯酚

2-硝基-4-氨基苯酚名称

[ CAS 号 ]:
119-34-6

[ 中文名 ]:
2-硝基-4-氨基苯酚

[ 英文名 ]:
2-nitro-4-aminophenol

[中文别名 ]:

[英文别名 ]:

2-hydroxy-5-aminonitrobenzene
5-amino-2-hydroxynitrobenzene
Phenol, 4-amino-2-nitro-
4-hydroxy-3-nitroaniline
4-Amino-2-nitrophenol
cioxidationbase25
2-nitro-4-aminophenol
fourrinebrownpr
fourrinebrownpropyl
EINECS 204-316-1

2-硝基-4-氨基苯酚物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
334.5±27.0 °C at 760 mmHg

[ 熔点 ]:
125-127 °C(lit.)

[ 分子式 ]:
C₆H₆N₂O₃

[ 分子量 ]:
154.123

[ 闪点 ]:
156.1±23.7 °C

[ 精确质量 ]:
154.037842

[ PSA ]:
92.07000

[ LogP ]:
0.64

[ 外观性状 ]:
暗褐色的晶体粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.689

[ 储存条件 ]:
室温，干燥

2-硝基-4-氨基苯酚MSDS

2-硝基-4-氨基苯酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SJ6303000

CHEMICAL NAME :: Phenol, 4-amino-2-nitro-

CAS REGISTRY NUMBER :: 119-34-6

BEILSTEIN REFERENCE NO. :: 1368435

LAST UPDATED :: 199701

DATA ITEMS CITED :: 23

MOLECULAR FORMULA :: C6-H6-N2-O3

MOLECULAR WEIGHT :: 154.14

WISWESSER LINE NOTATION :: ZR DQ CNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1470 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 302 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1470 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 108 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 7680 ug/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 12(Suppl 13),37,1988 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,43,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,43,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-GERMANY;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1706 No. of Facilities: 1356 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 11981 (estimated) No. of Female Employees: 9309 (estimated)

2-硝基-4-氨基苯酚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25-S37/39-S26

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
SJ6303000

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2922299090

2-硝基-4-氨基苯酚合成路线

2-硝基-4-氨基苯酚上下游产品

2-硝基-4-氨基苯酚上游产品

2-硝基-4-氨基苯酚下游产品

2-硝基-4-氨基苯酚海关

[ 海关编码 ]: 2922299090

[ 中文概述 ]:
2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2-硝基-4-氨基苯酚文献

Percutaneous absorption of nitroaromatic compounds: in vivo and in vitro studies in the human and monkey.

J. Invest. Dermatol. 84(3) , 180-3, (1985)

The percutaneous absorption of 2-nitro-p-phenylene-diamine, 4-amino-2-nitrophenol, nitrobenzene, p-nitroaniline, and 2,4-dinitrochlorobenzene was measured through human and monkey skin. Human studies ...

Plasma levels and kinetic disposition of 2,4-dinitrophenol and its metabolites 2-amino-4-nitrophenol and 4-amino-2-nitrophenol in the mouse.

J. Chromatogr. A. 344 , 177-86, (1985)

Eleven groups of six ICR mice were dosed orally with 22.5 mg/kg 2,4-dinitrophenol. Groups were sacrificed at 0, 0.5, 1, 2, 4, 6, 9, 12, 24, 48, and 96 h post-treatment and plasma was collected for ana...

The nonmutagenicity of purified 4-amino-2-nitrophenol in Salmonella typhimurium.

Carcinogenesis 3(7) , 809-13, (1982)

Two samples of 4-amino-2-nitrophenol were tested for mutagenicity in Salmonella typhimurium strains TA1535, TA1537, TA1538, TA98, and TA100. Significant mutagenic activity was detected with a sample o...

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